Methylophiopogonone...

Methylophiopogonone B
Methylophiopogonone B
Methylophiopogonone B
Methylophiopogonone B
Methylophiopogonone B

Methylophiopogonone B

Min.Order / FOB Price:Get Latest Price

10 Milligram

Negotiable

  • Min.Order :10 Milligram
  • Purity: ≥98%
  • Payment Terms : T/T

Keywords

Methylophiopogonone B 74805-89-3 standard supplier in China

Quick Details

  • Appearance:detailed see specifications
  • Application:analysis,activity test,Botanical Reference Materials,Standard materials
  • PackAge:According to the clients requirement.
  • ProductionCapacity:1|Metric Ton|Day
  • Storage:Store at 2~8°C
  • Transportation:by air or by ocean shipping

Superiority:

Hubei CuiRan Biotechnology Co., Ltd is a leading company in the research, development, manufacture and marketing of High Quality Phytochemicals and Extracts(especially Active Ingredients from Traditional Chinese Medicine,Traditional Chinese Medicine), Natural Active Pharmaceutical Ingredients worldwide. From small quantities for R&D or reference standard, to large quantities for customizing or manufacturing, Biopurify emphasizes on consistent and reliable services for his customers. 
With excellent quality products and good service, we have clients from more than dozens countries and regions, and we pride ourselves in providing our customers with a total satisfaction experiences.
We are doing our best to be your reliable partner for high quality Phytochemicals and Reference Standards from china.
 
Our main services:
A. Supply active ingredients and reference standards ofTraditional Chinese Medicine, from mgs to kgs scale.
B. Custom extraction and purification, target Herb Active Ingredients
C. Custom synthesis and semi-synthesis for Natural Active Ingredients
D. CR, CM and PD services from lab scale, pilot scale to commercial scale(GMP is also available)
E.Traditional Chinese Medicine compounds library
 

1.Provide traditional Chinese medicine reference materials and natural active ingredients;
2.More than 2200 compounds are available for selection, continuously building high-quality natural product libraries for drug research and development;
3.Provide various screening libraries and more inhibitor products;
4.Provide separation and structural determination of natural products;
5.Laboratory scale pilot to commercial scale collaborative research and process development services.More than 180 experiences in phytochemistry (still increasing)
Each product has passed very strict testing (NMR/MS/HPLC)
Agents from many countries

General tips:For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging:1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition:Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Details:

Chemical Properties of Methylophiopogonone B

Cas No. 74805-89-3    
PubChem ID 23259413 Appearance Powder
Formula C19H18O5 M.Wt 326.34
Type of Compound Flavonoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name 5,7-dihydroxy-3-[(4-methoxyphenyl)methyl]-6,8-dimethylchromen-4-one
SMILES CC1=C(C2=C(C(=C1O)C)OC=C(C2=O)CC3=CC=C(C=C3)OC)O
Standard InChIKey BUTFXZVBLOLETI-UHFFFAOYSA-N
Standard InChI InChI=1S/C19H18O5/c1-10-16(20)11(2)19-15(17(10)21)18(22)13(9-24-19)8-12-4-6-14(23-3)7-5-12/h4-7,9,20-21H,8H2,1-3H3
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Methylophiopogonone B

The roots of Ophiopogon japonicus

Biological Activity of Methylophiopogonone B

Description Methylophiopogonone B is a natural product from Ophiopogon japonicus.

Protocol of Methylophiopogonone B

Structure Identification

Zhongguo yao xue za zhi,2005,40(5):337-341.

Studies on the liposoluble components from tuber of Ophiopogon japonicus.[Reference: WebLink]


METHODS AND RESULTS:
The compounds were isolated by column chromatography with silica gel and Sephadex LH-20 and the structures were elucidated by spectras' analysis. Sixteen compounds were obtained as 7 homoisoflavones, 2 anthraquinones, 3 phenolic acids, 2 terpenes and 2 fatty acids. Their structures were identified as methylophiopogonanone A(I), methylophiopogonanone B(II), methylophiopogonone A(III), Methylophiopogonone B(IV), 2'-hydroxy-methylophiopogonone A(V), 6-aldehycto-isoophiopogo-nanone A(VI), 5,7-dihyelroxy-8-methoxy-6-methyl-3-(2'-hydroxy-4'-methoxybenzyl) chroman-4-one(VII), chrysophenol(VIII), emodin(IX), vanillic acid(X), P-hydroxy benzaldenhyde (XI), P-trans-coumarinic acid(XII), l-borneol-#beta#-D-glucopyranoside (XIII), oleanolia acid(XIV), azelaic acid (XV) and n-tricosanoic acid(XVI).
CONCLUSIONS:
The compound IV, VIII--XII and XIV--XVI were isolated from O. japonicus and the genus Ophiopogon for the first time, respectively. The types of anthraquinone, phenolic acid and triterpene were firstly obtained from the genus.

Preparing Stock Solutions of Methylophiopogonone B

  1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.0643 mL 15.3214 mL 30.6429 mL 61.2858 mL 76.6072 mL
5 mM 0.6129 mL 3.0643 mL 6.1286 mL 12.2572 mL 15.3214 mL
10 mM 0.3064 mL 1.5321 mL 3.0643 mL 6.1286 mL 7.6607 mL
50 mM 0.0613 mL 0.3064 mL 0.6129 mL 1.2257 mL 1.5321 mL
100 mM 0.0306 mL 0.1532 mL 0.3064 mL 0.6129 mL 0.7661 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

 

References on Methylophiopogonone B

Studies on the liposoluble components from tuber of Ophiopogon japonicus.

Zhongguo yao xue za zhi,2005,40(5):337-341.

The compounds were isolated by column chromatography with silica gel and Sephadex LH-20 and the structures were elucidated by spectras' analysis. Sixteen compounds were obtained as 7 homoisoflavones, 2 anthraquinones, 3 phenolic acids, 2 terpenes and 2 fatty acids. Their structures were identified as methylophiopogonanone A(I), methylophiopogonanone B(II), methylophiopogonone A(III), Methylophiopogonone B(IV), 2'-hydroxy-methylophiopogonone A(V), 6-aldehycto-isoophiopogo-nanone A(VI), 5,7-dihyelroxy-8-methoxy-6-methyl-3-(2'-hydroxy-4'-methoxybenzyl) chroman-4-one(VII), chrysophenol(VIII), emodin(IX), vanillic acid(X), P-hydroxy benzaldenhyde (XI), P-trans-coumarinic acid(XII), l-borneol-#beta#-D-glucopyranoside (XIII), oleanolia acid(XIV), azelaic acid (XV) and n-tricosanoic acid(XVI). The compound IV, VIII--XII and XIV--XVI were isolated from O. japonicus and the genus Ophiopogon for the first time, respectively. The types of anthraquinone, phenolic acid and triterpene were firstly obtained from the genus.

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