Sulforafan 4478-93-7 standard supplier in China
Hubei CuiRan Biotechnology Co., Ltd is a leading company in the research, development, manufacture and marketing of High Quality Phytochemicals and Extracts(especially Active Ingredients from Traditional Chinese Medicine,Traditional Chinese Medicine), Natural Active Pharmaceutical Ingredients worldwide. From small quantities for R&D or reference standard, to large quantities for customizing or manufacturing, Biopurify emphasizes on consistent and reliable services for his customers.
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General tips:For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging:1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition:Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.
Cas No. | 4478-93-7 | SDF | |
PubChem ID | 5350 | Appearance | White powder |
Formula | C6H11NOS2 | M.Wt | 177.29 |
Type of Compound | Miscellaneous | Storage | Desiccate at -20°C |
Solubility | DMSO : ≥ 62.5 mg/mL (352.53 mM) *"≥" means soluble, but saturation unknown. |
||
Chemical Name | 1-isothiocyanato-4-methylsulfinylbutane | ||
SMILES | CS(=O)CCCCN=C=S | ||
Standard InChIKey | SUVMJBTUFCVSAD-UHFFFAOYSA-N | ||
Standard InChI | InChI=1S/C6H11NOS2/c1-10(8)5-3-2-4-7-6-9/h2-5H2,1H3 | ||
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
||
About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
||
Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. |
The seeds of Brassica oleracea L. var. botrytis L.
Description | 1. Sulforaphane is a cruciferous vegetable-derived isothiocyanate with promising chemopreventive and therapeutic activities. 2. Sulforaphane might exert a significant neuroprotective effect on cholinergic deficit and cognitive impairment. 3. Sulforaphane has anti-inflammatory effect, at least ,in part,associated with interfering with the NF-κB pathway. 4. Sulforaphane inhibits TPA-induced NF-κB activation and COX-2 expression in MCF-10A cells by blocking two distinct signaling pathways mediated by ERK1/2-IKKα and NAK-IKKβ. 5. Sulforaphane has antitumor effects gainst bladder cancer cells through an ROS-mediated intrinsic apoptotic pathway, and suggest that ER stress and Nrf2 may represent strategic targets for Sulforaphane-induced apoptosis. |
Targets | Akt | ERK | TNF-α | p65 | NF-kB | IkB | COX | Nrf2 | HO-1 | Bcl-2/Bax | Caspase | AChR | IKK |
1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
1 mM | 5.6405 mL | 28.2024 mL | 56.4048 mL | 112.8095 mL | 141.0119 mL |
5 mM | 1.1281 mL | 5.6405 mL | 11.281 mL | 22.5619 mL | 28.2024 mL |
10 mM | 0.564 mL | 2.8202 mL | 5.6405 mL | 11.281 mL | 14.1012 mL |
50 mM | 0.1128 mL | 0.564 mL | 1.1281 mL | 2.2562 mL | 2.8202 mL |
100 mM | 0.0564 mL | 0.282 mL | 0.564 mL | 1.1281 mL | 1.4101 mL |
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. |
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