manufactory supply Flumazenil cas#78755-81-4

Details:

1.1 Name

Flumazenil

1.2 Synonyms

4H-Imidazo(1,5-a)(1,4)benzodiazepine-3-carboxylic acid, 8-fluoro-5,6-dihydro-5-methyl-6-oxo-, ethyl ester4H-IMIDAZO[1,5-A][1,4]BENZODIAZEPINE-3-CARBOXYLIC ACID, 8-FLUORO-5,6-DIHYDRO-5-METHYL-6-OXO-, ETHYL ESTER8-FLUORO-5,6-DIHYDRO-5-METHYL-6-OXO-4H-IMIDAZO[1,5-A][1,4]BENZODIAZEPINE-3-CARBOXYLIC ACID ETHYL EST8-FLUORO-5,6-DIHYDRO-5-METHYL-6-OXO-4H-IMIDAZO[1,5-A][1,4]BENZO-DIAZEPINE-3-CARBOXYLIC ACID ETHYL ESTER8-Fluoro-5,6-dihydro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylic acid ethyl esterAnexateEthyl 8-fluoro-5-methyl-6-oxo-5,6-dihydro-4H-benzo[f]imidazo[1,5-a][1,4]diazepine-3-carboxylateethyl 8-fluoro-5-methyl-6-oxo-5,6-dihydro-4h-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylateEthyl-8-fluoro-5,6-dihydro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylateFluMazenil USPFlumazepilFlumenazilFMZLanexatMaziconMFCD00242764Ro 15 1788Ro 151788RO 15-1788Ro 15-1788/000Ro 1722Ro 41-8157Ro-15-1788RO15-1788RomaziconYM-684

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1.3 CAS No.

78755-81-4

1.4 CID

3373

1.5 EINECS(EC#)

616-650-9

1.6 Molecular Formula

C15H14FN3O3 (isomer)

 

1.7 Inchi

1.8 InChIkey

OFBIFZUFASYYRE-UHFFFAOYSA-N

1.9 Canonical Smiles

CCOC(=O)C1=C2CN(C(=O)C3=C(N2C=N1)C=CC(=C3)F)C

1.10 Isomers Smiles

CCOC(=O)C1=C2CN(C(=O)C3=C(N2C=N1)C=CC(=C3)F)C

2. Properties

2.1 Density

1.39

2.1 Melting point

201-203℃

2.1 Boiling point

528 °C at 760 mmHg

2.1 Refractive index

1.633

2.1 Flash Point

273.1 °C

2.1 Vapour Pressure

0.0±1.4 mmHg at 25°C

2.2 Precise Quality

303.10200

2.2 PSA

64.43000

2.2 logP

1.71160

2.2 Solubility

Soluble in DMSO to 25mM

2.3 Appearance

Colourless crystals

2.4 Storage

2-8°C

2.5 Chemical Properties

Colourless crystals

2.6 Color/Form

white

2.7 pKa

0.86±0.20(Predicted)

2.8 Water Solubility

128 mg/L

 

2.9 StorageTemp

2-8°C

3. Use and Manufacturing

3.1 Definition

ChEBI: An organic heterotricyclic compound that is 5,6-dihydro-4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted at positions 3, 5, 6, and 8 by ethoxycarbonyl, methyl, oxo, and fluoro groups, respectively. It is used as an ntidote to benzodiazepine overdose.