Bromhexine hydrochloride 611-75-6 99%purity
Bromhexine hydrochloride Basic information
Product Name: Bromhexine hydrochloride
Synonyms: 2-AMINO-3,5-DIBROMO-N-CYCLOHEXYL-N-METHYLBENZY-LAMINE HYDROCHLORIDE;n-(2-amino-3,5-dibromobenzyl)-n-methylcyclohexylamine hydrochloride;2-amino-3,5-dibromo-n-cyclohexyl-n-methyl-benzenemethanaminmonohydrochlo;2-amino-n-cyclohexyl-3,5-dibromo-n-methylbenzylaminehydrochloride;2-amino-n-cyclohexyl-3,5-dibromo-n-methyl-benzylaminhydrochloride;bisolvon;bisolvonhydrochloride;bromessina
CAS: 611-75-6
MF: C14H21Br2ClN2
MW: 412.59
EINECS: 210-280-8
Product Categories: ROCEPHIN;Amines;Aromatics;Intermediates & Fine Chemicals;Pharmaceuticals;611-75-6
Mol File: 611-75-6.mol
Bromhexine hydrochloride Chemical Properties
Melting point 240-244 °C
storage temp. Sealed in dry,Room Temperature
solubility Very slightly soluble in water, slightly soluble in alcohol and in methylene chloride.
form powder
color White to Light Beige
λmax 307nm(Decane)(lit.)
Merck 14,1391
BRN 4848376
InChIKey UCDKONUHZNTQPY-UHFFFAOYSA-N
LogP 5.081 (est)
CAS DataBase Reference 611-75-6(CAS DataBase Reference)
Safety Information
Hazard Codes Xn
Risk Statements 20/21/22-36/37/38
Safety Statements 22-24/25-36-26
WGK Germany 2
RTECS XS9950000
HS Code 29215990
Description Bromhexine Hydrochloride is the hydrochloride salt form of bromhexine, a secretolytic, with mucolytic activity. Upon administration, bromhexine increases lysosomal activity and enhances hydrolysis of acid mucopolysaccharide polymers in the respiratory tract. This increases the production of serous mucus in the respiratory tract, which makes the phlegm thinner and decreases mucus viscosity. This contributes to its secretomotoric effect, and allows the cilia to more easily transport the phlegm out of the lungs. This clears mucus from the respiratory tract and may aid in the treatment of respiratory disorders associated with abnormal viscid mucus, excessive mucus secretion and impaired mucus transport.
Chemical Properties White Solid
Uses Bromhexine hydrochloride was used in the secretion of pancreatic juice of low viscosity.
Uses Bromhexine hydrochloride is a mucolytic agent used in the treatment of respiratory disorders associated with viscid or excessive mucus.
Bromhexine hydrochloride belongs to the group of expectorants (mucoactive agents). The active substance has a secretolytic effect. It is used for the treatment of strong cough, e.g. triggered by a bronchitis.
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