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Abiraterone Acetate Abiraterone Acetate powder Abiraterone
Hubei Yuanmeng Biological Technology Co., Ltd., which is located in Wuhan, China. We are specializing in the exportation of APIs, and plant extracts ect.
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Abiraterone Acetate
Product Name: Abiraterone acetate
CAS: 154229-18-2
MF: C26H33NO2
MW: 391.55
EINECS: 620-314-7
Melting point: 127-130°C
Boiling point: 506.7±50.0 °C
Density: 1.14±0.1 g/cm3
Storage temp.: -20°C
Appearance: White to Beige Powder
Description:
In April 2011, the United States FDA approved abiraterone acetate (CB7630) in combination with the steroid prednisone for the treatment of metastatic castration-resistant prostate cancer (mCRPC) for patients who were previously treated with a docetaxel containing regimen for late-stage disease. Abiraterone acetate affects prostate, testicular, and adrenal androgens by irreversibly inhibiting both the lyase and hydroxylase activity of cytochrome P450 17A (CYP17) signaling pathways (IC50's of 2.9 and 4 nM, respectively) thereby decreasing testosterone levels.
Uses:
Abiraterone acetate is a novel steroidal inhibitor of human Cytochrome P450 (17α-Hydroxylase-C17,20-lyase): potential agent for the treatment of prostatic cancer.
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Hubei Yuanmeng Biological Technology Co., Ltd.
Room 3820, Building 2, Vanke Golden City, Hongshan District, Wuhan, Hubei, China
Fiona Wei / Sales Manager
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