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Famciclovir Famciclovir powder China Famciclovir
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Famciclovir
Product Name: Famciclovir
CAS: 104227-87-4
MF: C14H19N5O4
MW: 321.33
EINECS: 630-411-6
Melting point: 102-104°C
Boiling point: 550.2±60.0 °C
Density: 1.40±0.1 g/cm3
Storage temp.: 2-8°C
Appearance: white to off-white powder
Description:
Famciclovir, an effective oral prodrug of the antiviral penciclovir, was launched in the UK and shortly after in the U.S.A. for the treatment of shingles (herpes zoster). As the diacetyl ester of the 6-deoxy- penciclovir, famciclovir has significantly improved oral absorption. It is converted to penciclovir in vivo with a bioavailability of 41 % in rats. Penciclovir is phosphorylated, and hence activated onty in herpesvirus infected cells. This stable metabolite, penciclovir-triphosphate, is a strong inhibitor of herpesvirus DNA polymerases and of viral DNA synthesis with long lasting effects. The high selectivity of famciclovir/penciclovir to herpes family of viruses and their rather low toxicity may make this agent superior to other existing drugs.
Uses:
Used as an antiviral. Prodrug of Penciclovir (P221500).
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Hubei Yuanmeng Biological Technology Co., Ltd.
Room 3820, Building 2, Vanke Golden City, Hongshan District, Wuhan, Hubei, China
Fiona Wei / Sales Manager
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