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Pimobendan Pimobendan powder China Pimobendan
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Pimobendan
Product Name: Pimobendan
CAS: 74150-27-9
MF: C19H18N4O2
MW: 334.37
EINECS: 640-420-7
Melting point: approximate 243℃ (dec.)
Density: 1.36
Storage temp.: 2-8°C
Appearance: white to beige powder
Description:
Pimobendan, a novel cardiotonic vasodilator, was introduced in Japan for the treatment of acute and mild to moderate chronic heart failure. It is a phosphodiesterase Ⅲ inhibitor and is able to enhance sensitization of myocardial contractile regulatory protein to calcium ions. The combination of these effects contribute to its inotropic activity.
Uses:
Pimobendan is a cardiotonic agent. The study of the cardiotonic mechanism of Pimobendan using ventricular muscles from rabbits and guinea pigs suggests that Pimobendan acts by inhibiting phosphodiesterase III and potassium channel. The potent venodilating action of Pimobendan makes it a suitable treatment option for patients with congestive heart failure (CHF) as it also improves systemic vasoconstriction.
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Hubei Yuanmeng Biological Technology Co., Ltd.
Room 3820, Building 2, Vanke Golden City, Hongshan District, Wuhan, Hubei, China
Fiona Wei / Sales Manager
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