,1-Dimethylbiguanid...

,1-Dimethylbiguanide hydrochloride
,1-Dimethylbiguanide hydrochloride
,1-Dimethylbiguanide hydrochloride
,1-Dimethylbiguanide hydrochloride
,1-Dimethylbiguanide hydrochloride

,1-Dimethylbiguanide hydrochloride

Min.Order / FOB Price:Get Latest Price

10 Milligram

Negotiable

  • Min.Order :10 Milligram
  • Purity: 98%

Keywords

,1-Dimethylbiguanide hydrochloride 1115-70-4 standard supplier in China

Quick Details

  • Appearance:detailed see specifications
  • Application:analysis,activity test,Botanical Reference Materials,Standard materials
  • PackAge:According to the clients requirement.
  • ProductionCapacity:1|Metric Ton|Day
  • Storage:Store at 2~8°C
  • Transportation:by air or by ocean shipping

Superiority:

Hubei CuiRan Biotechnology Co., Ltd is a leading company in the research, development, manufacture and marketing of High Quality Phytochemicals and Extracts(especially Active Ingredients from Traditional Chinese Medicine,Traditional Chinese Medicine), Natural Active Pharmaceutical Ingredients worldwide. From small quantities for R&D or reference standard, to large quantities for customizing or manufacturing, Biopurify emphasizes on consistent and reliable services for his customers. 
With excellent quality products and good service, we have clients from more than dozens countries and regions, and we pride ourselves in providing our customers with a total satisfaction experiences.
We are doing our best to be your reliable partner for high quality Phytochemicals and Reference Standards from china.
 
Our main services:
A. Supply active ingredients and reference standards ofTraditional Chinese Medicine, from mgs to kgs scale.
B. Custom extraction and purification, target Herb Active Ingredients
C. Custom synthesis and semi-synthesis for Natural Active Ingredients
D. CR, CM and PD services from lab scale, pilot scale to commercial scale(GMP is also available)
E.Traditional Chinese Medicine compounds library


1.Provide traditional Chinese medicine reference materials and natural active ingredients;
2.More than 2200 compounds are available for selection, continuously building high-quality natural product libraries for drug research and development;
3.Provide various screening libraries and more inhibitor products;
4.Provide separation and structural determination of natural products;
5.Laboratory scale pilot to commercial scale collaborative research and process development services.More than 180 experiences in phytochemistry (still increasing)
Each product has passed very strict testing (NMR/MS/HPLC)
Agents from many countries

General tips:For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging:1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition:Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Details:

Chemical Properties of Metformin HCl

Cas No. 1115-70-4 SDF  
PubChem ID 14219 Appearance Powder
Formula C4H12ClN5 M.Wt 165.62
Type of Compound N/A Storage Desiccate at -20°C
Synonyms 1,1-Dimethylbiguanide hydrochloride
Solubility H2O : ≥ 32 mg/mL (193.21 mM)
DMSO : ≥ 1.7 mg/mL (10.26 mM)
*"≥" means soluble, but saturation unknown.
Chemical Name N,N-Dimethylimidodicarbonimidic diamide hydrochloride
SMILES [H+].[Cl-].CN(C)C(=N)N=C(N)N
Standard InChIKey OETHQSJEHLVLGH-UHFFFAOYSA-N
Standard InChI InChI=1S/C4H11N5.ClH/c1-9(2)4(7)8-3(5)6;/h1-2H3,(H5,5,6,7,8);1H
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Biological Activity of Metformin HCl

Description Antidiabetic agent; lowers plasma glucose levels and improves insulin sensitivity. Inhibits hepatic gluconeogenesis via activation of the LKB1/AMPK pathway. Displays antiproliferative effects in cancer cell lines. Activates the aPKC-CBP pathway in neural precursors to promote neurogenesis. Activates autophagy.

Preparing Stock Solutions of Metformin HCl

  1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 6.0379 mL 30.1896 mL 60.3792 mL 120.7584 mL 150.948 mL
5 mM 1.2076 mL 6.0379 mL 12.0758 mL 24.1517 mL 30.1896 mL
10 mM 0.6038 mL 3.019 mL 6.0379 mL 12.0758 mL 15.0948 mL
50 mM 0.1208 mL 0.6038 mL 1.2076 mL 2.4152 mL 3.019 mL
100 mM 0.0604 mL 0.3019 mL 0.6038 mL 1.2076 mL 1.5095 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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