3',5'-cyclic AMP

3',5'-cyclic AMP
3',5'-cyclic AMP
3',5'-cyclic AMP
3',5'-cyclic AMP
3',5'-cyclic AMP

3',5'-cyclic AMP

Min.Order / FOB Price:Get Latest Price

10 Milligram

Negotiable

  • Min.Order :10 Milligram
  • Purity: 98%

Keywords

3',5'-cyclic AMP 60-92-4 standard supplier in China

Quick Details

  • Appearance:detailed see specifications
  • Application:analysis,activity test,Botanical Reference Materials,Standard materials
  • PackAge:According to the clients requirement.
  • ProductionCapacity:1|Metric Ton|Day
  • Storage:Store at 2~8°C
  • Transportation:by air or by ocean shipping

Superiority:

Hubei CuiRan Biotechnology Co., Ltd is a leading company in the research, development, manufacture and marketing of High Quality Phytochemicals and Extracts(especially Active Ingredients from Traditional Chinese Medicine,Traditional Chinese Medicine), Natural Active Pharmaceutical Ingredients worldwide. From small quantities for R&D or reference standard, to large quantities for customizing or manufacturing, Biopurify emphasizes on consistent and reliable services for his customers. 
With excellent quality products and good service, we have clients from more than dozens countries and regions, and we pride ourselves in providing our customers with a total satisfaction experiences.
We are doing our best to be your reliable partner for high quality Phytochemicals and Reference Standards from china.
 
Our main services:
A. Supply active ingredients and reference standards ofTraditional Chinese Medicine, from mgs to kgs scale.
B. Custom extraction and purification, target Herb Active Ingredients
C. Custom synthesis and semi-synthesis for Natural Active Ingredients
D. CR, CM and PD services from lab scale, pilot scale to commercial scale(GMP is also available)
E.Traditional Chinese Medicine compounds library


1.Provide traditional Chinese medicine reference materials and natural active ingredients;
2.More than 2200 compounds are available for selection, continuously building high-quality natural product libraries for drug research and development;
3.Provide various screening libraries and more inhibitor products;
4.Provide separation and structural determination of natural products;
5.Laboratory scale pilot to commercial scale collaborative research and process development services.More than 180 experiences in phytochemistry (still increasing)
Each product has passed very strict testing (NMR/MS/HPLC)
Agents from many countries

General tips:For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging:1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition:Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Details:

Chemical Properties of Adenosine cyclophosphate

Cas No. 60-92-4 SDF  
PubChem ID 274 Appearance Powder
Formula C10H12N5O6P M.Wt 329.21
Type of Compound Miscellaneous Storage Desiccate at -20°C
Solubility H2O : ≥ 5 mg/mL (15.19 mM)
DMSO : < 1 mg/mL (insoluble or slightly soluble)
*"≥" means soluble, but saturation unknown.
Chemical Name 6-(6-aminopurin-9-yl)-2-hydroxy-2-oxo-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-7-ol
SMILES C1C2C(C(C(O2)N3C=NC4=C3N=CN=C4N)O)OP(=O)(O1)O
Standard InChIKey IVOMOUWHDPKRLL-UHFFFAOYSA-N
Standard InChI InChI=1S/C10H12N5O6P/c11-8-5-9(13-2-12-8)15(3-14-5)10-6(16)7-4(20-10)1-19-22(17,18)21-7/h2-4,6-7,10,16H,1H2,(H,17,18)(H2,11,12,13)
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Biological Activity of Adenosine cyclophosphate

Description Adenosine cyclophosphate combined with vitamin C treatment of children with viral myocarditis has exact curative effect,and it can improve cardiac function of patients and improve immune function. Combined Puerarin with meglumine adenosine cyclophosphate in treating refractory heart failure is effective and safe.
Targets cAMP | PDE | Histone Methyltransferase | PGE
In vivo

Clinical observation on effect of Puerarin combined with meglumine adenosine cyclophosphate in treatment of refractory heart failure[Reference: WebLink]

Chinese Journal of Integrated Traditional and Western Medicine in Intentire Critical Care,2003 ,39 (14):3263-79.

To explore the clinical effect of Puerarin combined with meglumine Adenosine cyclophosphate in treatment of refractory heart failure.
METHODS AND RESULTS:
Sixtytwo cases with refractory heart failure were randomly divided into control group( n =30) and treatment group ( n =32). The control group was treated with routine therapy including oxygen inhalation, diuretic, digitalis, vasodilator, angiotensin converting enzyme inhibitor(ACEI), antibiotic therapy, and supporting treatment. The treatment group was treated with Puerarin 0.4 g+5% glucose 250 ml intravenously drip once a day for 14 days, meglumine Adenosine cyclophosphate 120 mg+5% glucose 250 ml intravenously, drip once a day for 14 days, as well as routine therapy. After two weeks, the clinical effects were compared between two groups. The heart function and cardiac indexes were improved after treatment in two groups (all P 0.01), the difference was significant between treatment group and control group after treatment ( P 0.05).
CONCLUSIONS:
Combined Puerarin with meglumine Adenosine cyclophosphate in treating refractory heart failure is effective and safe.

Adenosine cyclophosphate combined with vitamin C treatment of children with viral myocarditis and the effect on cellular immune function[Reference: WebLink]

Journal of Hainan Medical University , 2016 ,22 (11) :1112-4.

To investigate the curative effect of Adenosine cyclophosphate combined with vitamin C on children with viral myocarditis and its effect on cellular immune function.
METHODS AND RESULTS:
A total of 96 cases of children with viral myocarditis were randomly divided into control group and observation group,48 cases in each.The control group received routine treatment for viral myocarditis.The observation group received routine treatment for viral myocarditis as well as vitamin C and Adenosine cyclophosphate.
CONCLUSIONS:
Adenosine cyclophosphate combined with vitamin C treatment of children with viral myocarditis has exact curative effect,and it can improve cardiac function of patients and improve immune function.

Preparing Stock Solutions of Adenosine cyclophosphate

  1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.0376 mL 15.1879 mL 30.3757 mL 60.7515 mL 75.9394 mL
5 mM 0.6075 mL 3.0376 mL 6.0751 mL 12.1503 mL 15.1879 mL
10 mM 0.3038 mL 1.5188 mL 3.0376 mL 6.0751 mL 7.5939 mL
50 mM 0.0608 mL 0.3038 mL 0.6075 mL 1.215 mL 1.5188 mL
100 mM 0.0304 mL 0.1519 mL 0.3038 mL 0.6075 mL 0.7594 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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