Factory price Concanavalin A CAS 11028-71-0 in stock

Details:

Factory price Concanavalin A CAS 11028-71-0 in stock

Details

Concanavalin A Basic information
Product Name:    Concanavalin A
Synonyms:    LECTIN FROM CANAVALIA ENSIFORMISTYPE IV- S GAMMA-IR;LECTIN CONCANAVALIN A FROM CANAVALIAENSI FORMIS FER;CONCANAVALIN A FROM CANAVALIAENSIFORMIS TYPE V;LECTIN FROM CONCANAVALIN A PEROXIDASE*LA BELED;LECTIN FROM CONCANAVALIN A TYPE VI;CONCANAVALIN A (CON A);concanavalin a from canavalia ensiformis (jack bean);CONCANAVALIN
CAS:    11028-71-0
MF:    C15H24
MW:    0
EINECS:    234-258-2
Product Categories:    reagent
Mol File:    Mol File
Concanavalin A Structure
Concanavalin A Chemical Properties
Fp     39 °C
storage temp.     -20°C
solubility     PBS: 5 mg/mL, slightly hazy
form     powder
Water Solubility     Slightly soluble in water and phosfate buffered saline.
CAS DataBase Reference    11028-71-0
Safety Information
Hazard Codes     Xn
Risk Statements     10-42/43-63-40-20/21/22
Safety Statements     36-24/25-45-36/37-23-22
RIDADR     UN 1170 3/PG 3
WGK Germany     3
RTECS     GK6890000
F     10-21
HS Code     35040090
MSDS Information
Provider    Language
SigmaAldrich    English
Concanavalin A Usage And Synthesis
Chemical Properties    Lyophilized
Uses    Concanavalin A is a unique lectin purified from the jack bean, C. ensiformis, that selectively cross-links cell-surface glycoproteins and affects the initiation of cell agglutination, mitogenesis, and apoptosis. Concanavalin A specifically binds to α-mannose and α-galactose structures found in sugars, glycoproteins, and glycolipids and has been used in affinity chromatography purifications of various glycoproteins and cellular structures. At 20 mg/kg concanavalin A is also used to induce liver injury in experimental mouse models of autoimmune hepatitis in order to study immune regulation by macrophages and T cells. Concanavalin A is toxic to several tumor cell lines and has been reported to induce programmed cell death of cortical neurons by a mechanism similar to that of the amyloid β peptide.
Uses    As a reagent in analytical and preparative biochemistry; as a probe in studies of cell surface membrane dynamics and cell division.
Uses    Concanavalin A is a plant lectin that is a T-cell mitogen, and induces apoptosis in human fibroblasts.
Definition    A lectin mitogen that binds specifically to and agglutinates transforms into tumors. It binds to glucose and mannose residues in the surface.
General Description    Concanavalin A is a protein containing only β-sheets in its structure, and belongs to the legume lectins family.
Hazard    Poison; teratogen; mutagen.
Biochem/physiol Actions    Concanavalin A is known to stimulate acute hepatic inflammation and acts as a T‐cell mitogen. It has inhibitory effect on hepatocellular carcinoma by inducing autophagy.
storage    -20°C

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