Angelica Root Extract Imperatorin CAS 482-44-0

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6. Package: Professional packing with professional materials.

 

 

Chemical Name: Imperatorin
CAS No.: 482-44-0

Chemical Structure: C16H14O4

Molecular weight: 270.28

Appearance: Light brown powder

Assay: 98%min

 

The imperatorin extracted from the dried roots of the genus Umbelliferae has been shown to have antibacterial,
antiasthmatic,antiallergic, dilated blood vessels, and inhibition of tumor cell proliferation. Lipid microspheres and liposomes are drug carriers prepared by using natural lipid materials such as phospholipids and cholesterol. With this carrier, drugs can be transported to the site of the lesions, and the drug molecules can be protected from degradation by biological enzymes. The pre-prescription study and drug stability test of imperatorin can provide a theoretical basis for the design optimization of the injection of imperatorin microspheres. The application of lipid microsphere technology to the study of imperatorin drugs can reduce the renal side effects of drugs under the precursors that maintain efficacy.

 

Function

Effect on the central nervous system

The effect of imperatorin on seizures was studied using the ma ximal electroconvulsive epileptic seizure threshold model in mice.The study found that intraperitoneal injection of 50 and 100 mg/kg-1 of imperatorin 30 minutes earlier could increase the voltage threshold of seizures in mice by 38% and 68%, respectively, and demonstrated that imperatorin improves mice with electrical stimulation. The effect of the onset threshold is dose and time dependent.

Effects on the cardiovascular system

The chromatographic retention peaks of imperatorin and verapamil were similar. It can reduce the protein content and cell volume of cardiomyocytes prestimulated by angiotensin I, and its effect is dose-dependent: the ratio of heart weight of spontaneously hypertensive rats treated with angiotensin I is significantly reduced, indicating that the effect of angiotensin I on both in vivo and in vitro is anti-hypertrophy.

Antibacterial and antiviral activity

Imperatorin has significant antibacterial and antiviral activity. Seven components were extracted from the flowers of Magydaris tomcntosa, and four components, including eucrutin, were tested for bacteriostasis. It was found that eucrutin had strong inhibitory activity against both gram-positive and gram-negative bacteria (minimum bacteriostasis concentration was 32-128 mg-ml).

Application

1.Common cold due to wind-cold pathogens manifested as headache, stuffy nose, etc;

2. Headache, toothache, especially pain in the forehead and superciliary region;

3. Various infections on the body surface. For the treatment of acute mastitis, it is often used with trichosanthes fruit, fritillary bulb and dandelion; for various kinds of sores and swellings, it is often used with honey suckle flower, trichosanthes fruit and other drugs;

4. Leukorrhagia. For patients with profuse clear and thin leukorrhea due to cold-dampness, this drug is often used with white atractylodes rhizome, poria and cuttlebone; for foul yellow thick leukorrhagia due to damp-heat, it is used with phellodendron bark, plantain seed and other drugs;

5. Stomachache. It can be used with liquorice, named Deoction of Dahurian Angelica and liquorice.

Companies adhering to the "pursuit of quality, innovation and development" business philosophy, to serve as a foundation, for the survival by the quality, seek development by science and technology, adhere to quilty comes first,fair price,good sense of customer service and responsibility. in the future hebei Nengqian import and export trade Co.,Ltd will always hold "integrity, innovation" business philosophy, to achieve honesty management, on the way of specialization, internationalization,  Keep moving!  

Our company specializes in processing and selling chemical raw materials, chemical products, pharmaceutical intermediates, veterinary medicine intermediates, dye intermediates, pigments, cosmetics raw materials and chemical reagents,  
Our company has a number of sales team, service and information feedback vertical integration of a sound marketing network, products are sold throughout the country and exported to South Asia, Europe, America, Africa and other more than 20 countries and regions.  

Packing:  
  1. Inner double plastic bags----25kg/Fiber drum (35*35*45cm, GW: 28kg, NW: 25kg); 

  2. Inner double plastic bags----5kg/Aluminum foil bag (GW: 6.5kg, NW: 5kg). 

  3. Inner double plastic bags----1kg/Aluminum foil bag (GW: 1.5kg, NW: 1kg). 

P.S.: we accept packaging customization. 

  
Delivery:   

  1. Stock products are normally shipping within 3 working days.  

  2. For rush delivery, please contact our sales team for particular arrangement. 

Shipping Details: 
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  2. Shipping details & shipping documents will be provided and sent by email. 

  3. We keep tracking the shippment until clients well received. 

  4. After years export shipping experience, with professional and experienced cooperated forwarders, we ensure that goods can be delivered in multiple ways safetly and efficiently. 

FAQ: 
1. Are you a trade company or factory   
We are a  factory with our own trading company.  

2. How do you control the quality   
   Our factory is equipped with professional technicians to control quality, out inspectors take sample for testing every 2 hours to ensure the quality of our production. We also accept BV, SGS or any other Third-party inspection.   
3.  How long is lead time  
   We deliver goods within 3 days for small order, 7-10 days for bulk order.   
4.  Where is your factory located How can I visit the factory   
    Our factory located in WEIFANG, China. It is only two hours from QINGDAO.  

6. Can i get some samples 
  Yes, we can supply free sample, but the shipping cost be paid by our customers. 

7. How to start orders or make payments 
  Proforma invoice will be sent first after confirmation of order, enclosed our bank information.Payment by T/T,  

8. How to confirm the Product Quality before placing orders 
  You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. 
  You can send us your product specifications and requests,we will manufacture the products according to your requests. 

9. How long is lead time

We deliver goods within 3 days for small order, 7-10 days for bulk order.

 

10. How do you treat quality complaint

  First of all, our quality control will reduce the quality problem to near zero. If there is a realquality problem caused by us, we will send you free goods for replacement or refund your loss.