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Calcipotriene Calcipotriene powder Pharmaceutical
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Calcipotriene
Product Name: Calcipotriene
CAS: 112965-21-6
MF: C27H40O3
MW: 412.6
EINECS: 601-218-4
Melting point: 166-168°C
Boiling point: 582.0±50.0 °C
Density: 1.12±0.1 g/cm3
Storage temp.: Desiccate at -20°C
Appearance: White Crystalline Powder
Description:
Calcipotriene also known as Calcipotriol, is a topical vitaminD3 derivative effective in the treatment of psoriasis vulgaris. The drug acts by binding to vitamin D3 receptors in the skin keratinocytes, producing an elevation in cell differentiation and a reduction in cell proliferation. Although its efficacy is comparable to calcitriol, calcipotriol exhibits at least 100 times less effect on calcium metabolism in rats.
Uses:
Calcipotriene is an antipsoriatic that is a vitamin D3 analogue with low calcemic activity. It works by regulating the production and growth of skin cells. In the United States, this drug was first marketed under the trade name Dovonex and is used mainly for the treatment of psoriasis. It is one of the most effective non glucocorticoid topical drugs for the treatment of localized psoriasis.This drug has many off-label applications that are alternative therapies for many dermatologic diseases.
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Hubei Yuanmeng Biological Technology Co., Ltd.
Room 3820, Building 2, Vanke Golden City, Hongshan District, Wuhan, Hubei, China
Fiona Wei / Sales Manager
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