High Activity Pepsin

Details:

 

High Activity Pepsin

Product Name:    Pepsin
Synonyms:    IMMOBILIZED PEPSIN;Pepsine from porcine (high activity, 1: 50000) lyophil.;Pepsin ,>0.7 Ph.Eur.U/Mg (activity);OMniTrace Ultra (TM) Perchloric Acid;Pepsin(porcine stoMach Mucose);BOVINEPEPSINB;AVIANPEPSIN;BOVINEPEPSINA
CAS:    9001-75-6
MF:    n.a.
MW:    0
EINECS:    232-629-3
Product Categories:    Enzymes;API
Mol File:    Mol File

 

 

 

 

   

Item	Specification	Standard
Apperance	white or light yellow amorphous powder	USP39
Identification	Conform	USP39
Solubility	Soluble in water , insoluble in ethanol and ether	USP39
Loss on drying	≤5.0%	USP39
Fat	≤6.0%	USP39
Microbial limit E.Coli Salmonella	Negative	USP39
Protease	Not less than 100 units/mg, calculated on the dried basis.	USP39
Amylase	Not less than 100 units/mg, calculated on the dried basis.	USP39
Lipase	Not less than 8 units/mg, calculated on the dried basis.	USP39

 

 

Medical research
Pepsin is utilized in regulation of digestion, as a dental antiseptic and in treatment of ailment including dyspepsia, gastralgia, obstinate vomiting, infantile diarrhea, apepsia and some cancer. Combined with HCl, pepsin tablets and capsules have been developed to support the digestibility in the gastrointestinal tract as well as to enhance the appetite of patients . Pepsin from porcine stomach is used for treatment of gastric ulcers with bismuth complexes added. Pepsin is also added for better digestibility of proteins in animals feed.
Pepsin is also commonly used in the preparation of F(ab')2 fragments from antibodies .

Cheese making
Animal (calf, bovine and porcine sources) rennet is composed of pepsin and chymosin commonly mixed in a ratio of 1:9 and used in commercial cheese making. During the food manufacturing process, pepsin is very useful in: modifying and providing whipping qualities to soy protein and gelatin, modifying vegetable proteins for use in nondairy snack items, making precooked cereals into instant hot cereals, and preparing animal and vegetable protein hydrolysates for use in flavoring foods and beverages.

Collagen extraction
Conventionally, collagen is extracted by an acid-solubilization process (ASP) in which collagen is solubilized in an acid (such as acetic acid) and other non-acid-soluble materials are removed. Since pepsin can break down cross-linkages in the telo peptide regions of collagen without harming to its secondary structure, the use of pepsin in this process can effectively enhance the yield of collagen.

Purification
The process of partitioning of pepsin commonly involves three steps: (a) extraction of pepsinogen which involves preparation of stomach and crude extract, (b) purification of pepsinogen and (c) activation of pepsinogen to pepsin. All these steps are conducted at low temperatures (≤ 4ºC) to prevent denaturation of proteins.

 

 

 

 

 

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Binbo Biological Co., Ltd. is located in the convenient transportation and beautiful scenery of Jining high-technology industrial zone - Jinxiang economic Development Zone. There is a 105 National road links north and south when Zaocao and Dongfeng Roads connect east and west. Besides, provincial expressway and Ji-Xu expressway which connect Beijing,Shanghai,Fuzhou, and several cities across the JinXiang economic development zone. More importantly, there are only 20 km to Jining airport and close to Qufu high-speed railway station.These convenient geographical conditions bring the development opportunities for this economic development zone.

Binbo Biological Products Co. Ltd., is a professional high-tech enterprise which engaged in Biological products and raw materials. Company was established in 2001, currently our company has more than 28 thousand square meters covering area. Factory buildings and workshops were establishsd by modern production requirements.There are three steps of development project which planned to invest around 60 million RMB. Currently the first step were finished and spent 28 million RMB, which met the production and office requirements.

Binbo is engaged in R&D with perfect equipments and advanced detecting instruments. The factory is in strict accordance with GMP standard in the course of design and construction.

 

 

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