CasNo.2030-63-9,Clofazimine, CAS No. 2030-63-9,(2030-63-9) Suppliers

1 Kilogram	FOB Price:USD 70.0000 -90.0000

Min.Order :1 Kilogram
Purity: >99%
Payment Terms : L/C,D/A,D/P,T/T,Other

Keywords

Clofaziminum [INN-Latin] 2-phenazinamine,3,5-dihydro-n,5-bis(4-chlorophenyl)-3-((1-methylethyl)imino);3-(p-chloranilino)-10-(p-chlorphenyl)-2,10-dihydro-2-(isopropylimino)-phenaz N,5-bis(4-chlorophenyl)-3-propan-2-yliminophenazin-2-amine

Quick Details

Appearance:Brick red crystalline powder.
Application:It is a rhimophenazine dye that was originally developed for the treatment of tuberculosis and has both antibacterial and anti-inflammatory activity
PackAge:Inside plastic outside
ProductionCapacity:200|Metric Ton|Week
Storage:Store in a cool and dry place
Transportation:We ship goods via DHL, Fedex, UPS, TNT, China post, NL Post and other couriers, weight from 10g to 1000kg or even bulker.?

Superiority:

With our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements.

Consistent Quality
Our plant has strict quality control in each manufacturing process. Guaranteed.
Meanwhile all the materials are tested before each shipment in our laboratory to double confirm the quality.

Most competitive pricing
Our company is committed to the production and development of titanium dioxide, we always offer the most competitive pricing to customers to help lower their cost in application.

Shortest delivery time
90% of orders are shipped within 7-10 days after receipt of the prepayment or workable L/C.

Respond in 24 hours to inquiry, feedback or other requirements
Our experienced staff is dedicated to answer all of your inquires, feedback or other requirements in 24 hours.

We welcome you to contact us for more information and look forward to working with yo

Details:

Our company specializes in processing and selling chemical raw materials, chemical products, pharmaceutical intermediates, veterinary medicine intermediates, dye intermediates, pigments, cosmetics raw materials and chemical reagents,
Our company has a number of sales team, service and information feedback vertical integration of a sound marketing network, products are sold throughout the country and exported to South Asia, Europe, America, Africa and other more than 20 countries and regions.
Companies adhering to the "pursuit of quality, innovation and development" business philosophy, to serve as a foundation, for the survival by the quality, seek development by science and technology, adhere to quilty comes first,fair price,good sense of customer service and responsibility. in the future hebei Nengqian import and export trade Co.,Ltd will always hold "integrity, innovation" business philosophy, to achieve honesty management, on the way of specialization, internationalization, Keep moving!
Our company's strengths：
1.Our products are superior in quality and competitive in price
2. Standard: BP/USP/EP/ enterprise standard
All purities ≥99%
3. Fast and safe delivery and careful delivery, a variety of transportation modes for your choice of service.A clearance rate of 99% or higher

Product Description:

name	Clofazimine
cas	2030-63-9
density	1.1342 (rough estimate)
refractive index	1.6300 (estimate)
stroage temp	2-8°C
melting point	210-212°
boiling point	616.26°C (rough estimate)
molecular formula	C27H22Cl2N4
molecular weight	473.4

Study
1.ClofazimineStimulates oxygen consumption and superoxide production by neutrophils. Clofazimine acts on neutrophils and activates phospholipase A2, resulting in increased release of lysophosphatidylcholine and arachidonic acid from neutrophils cell membranes. Clofazimine inhibits mitogen-induced stimulation of peripheral blood monocytes. Clofazimine can stabilize the lysosomal membrane of macrophages and inhibit the metabolism of M. leprae in mouse peritoneal macrophages. Clofazimine(5mg/mL) increased the dose-dependent activity of phospholipase A2 in s. aureus by increasing the release of 3h-radio-labeled arachidonic acid and lysophosphatidylethanolamine ([Chemicalbook3H]LPE) from bacterial membrane phospholipids. Clofazimine inhibited 90% of 20 MYCObacterium tuberculosis strains, MICs<1.0μg/mL, it should be noted that Clofazimine inhibited 2227 mycobacterium tuberculosis strain, MICs was 0.06μg/mL. Clofazimine(1μg/mL) dose-dependently inhibited the activity of J774A1 macrophages.

2.Clofazimine(20mg/kg) prevented death and was used on the lungs and spleen of C57BL/6 mice infected with mycobacterium tuberculosis H37Rv, resulting in a significant reduction in the number of CFU. LiposomalClofazimine(l-clf)(50mg/kg) was administered to acute infected mice with mycobacterium tuberculosis Erdman, and the CFU of spleen, liver and lungs was dose-dependent, with log as the unit of Chemicalbook 2-3. Clofazimine(500μg, twice-daily) resulted in the highest concentrations of Clofazimine in the spleen and liver of the mice, while Clofazimine concentration in the lungs was significantly reduced. Clofazimine(20mg/kg) effectively reduced bacterial load in the liver, spleen and lungs of C57BL/6 mice infected with mycobacterium avium strain TMC724.

Packing:
1. Inner double plastic bags----25kg/Fiber drum (35*35*45cm, GW: 28kg, NW: 25kg);

2. Inner double plastic bags----5kg/Aluminum foil bag (GW: 6.5kg, NW: 5kg).

3. Inner double plastic bags----1kg/Aluminum foil bag (GW: 1.5kg, NW: 1kg).

P.S.: we accept packaging customization.

Delivery:

1. Stock products are normally shipping within 3 working days.

2. For rush delivery, please contact our sales team for particular arrangement.

Shipping Details:
1. We ship goods via DHL, Fedex, UPS, TNT, China post, NL Post and other couriers, weight from 10g to 1000kg or even bulker.

2. Shipping details & shipping documents will be provided and sent by email.

3. We keep tracking the shippment until clients well received.

4. After years export shipping experience, with professional and experienced cooperated forwarders, we ensure that goods can be delivered in multiple ways safetly and efficiently.

FAQ:
Q1:Will you supply samples for testing
A: Free samples for the quality evaluation for most products, but customers only need to undertake the shipping fee for delivery the samples to your door.

Q2:What's your MOQ
A: For the high value product, our MOQ starts from 10g,100g and 1kg.

Q3:Which kind of payment terms do you accept
A: Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T, and BTC). Bulk order by T/T or L/C.

Q4:How about your delivery time
A: Generally, it will take 3 to 5 days after receiving your advance payment.

Q5:How do you treat quality complaint
A:First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.