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Artemether 71963-77-4 Artemether powder
Artemether
CAS: 71963-77-4
Molecular Formula: C16H26O5
Molecular Formula | C16H26O5 |
Molar Mass | 298.37 |
Density | 1.0733 (rough estimate) |
Melting Point | 86-88°C |
Boling Point | 359.79°C (rough estimate) |
Specific Rotation(α) | D19.5 +171° (c = 2.59 in CHCl3) |
Solubility | Easily soluble in acetone or chloroform. Soluble in ethanol or ethyl acetate, almost insoluble in water. |
Appearance | Colorless crystalline powder |
Color | off-white to light brown |
Merck | 14,815 |
Storage Condition | room temp |
Refractive Index | 1.6200 (estimate) |
MDL | MFCD00866205 |
Physical and Chemical Properties | White granular crystal, soluble in methanol, ethanol, DMSO and other organic solvents, derived from Artemisia annua leaves. |
Use | Used as an antimalarial drug |
introduction | artemether and bifluorenol are two new antimalarial drugs with different structures and functions successfully developed in recent years. Both drugs are usually treated with a single drug. The function of artemether is characterized by rapid killing of malaria parasites, but incomplete killing of insects, and the recovery rate of protozoa remaining in the patient's blood after treatment is high. |
traits | white crystal or crystalline powder, bitter and odorless. |
properties | this product is easily soluble in acetone and chloroform, soluble in ethanol or ethyl acetate, and almost insoluble in water. |
use | artemether has a direct killing effect on the red inner phase of plasmodium, has no effect on the tissue phase, has low toxicity to experimental animals, absorbs blocks in the body, has wide distribution and fast excretion. Electron microscope observation shows that the main part of the action of this product on Plasmodium murine is the membrane structure, and its anti-malarial mechanism is believed to interfere with the function of the surface membrane of Plasmodium. A methyl ether derivative of artemisinin. Used as antimalarial drug |
chemical properties | white granular crystal, soluble in methanol, ethanol, DMSO and other organic solvents, derived from Artemisia annua leaves. |
category | toxic substances |
toxicity classification | poisoning |
acute toxicity | oral-mouse LD50: 1000 mg/kg; Subcutaneous-mouse LD50: 390 mg/kg |
flammability hazard characteristics | combustible; combustion produces stimulating smoke |
storage and transportation characteristics | ventilation and low temperature drying |
fire extinguishing agent | dry powder, foam, sand, carbon dioxide, mist water |
Mol Download Chemical properties
CAS:
71963-77-4
MF:
C16H26O5
MW:
298.37
EINECS:
663-549-0
MDL No.:
MFCD00866205
Melting point:
86-88°C
alpha
D19.5 +171° (c = 2.59 in CHCl3)
Boiling point:
359.79°C (rough estimate)
Density
1.0733 (rough estimate)
refractive index
1.6200 (estimate)
storage temp.
room temp
solubility
DMSO: ≥20mg/mL
form
powder
color
off-white to light brown
optical activity
[α]/D +155 to +175°, c = 0.5 in methanol
Merck
14,815
Xi'an Eastling biotech Co., Ltd. is dedicated to the research and development, production, and sales of natural plant extracts; With nearly 15 years of experience in identifying, researching, developing, and producing active ingredients for medicinal plants, we focus on providing innovative products and services to customers in industries such as pharmaceuticals, health food, and cosmetics.
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