Top Quality Natural...

Top Quality Natural Dihydroartemisinin 98%
Top Quality Natural Dihydroartemisinin 98%
Top Quality Natural Dihydroartemisinin 98%
Top Quality Natural Dihydroartemisinin 98%

Top Quality Natural Dihydroartemisinin 98%

Min.Order / FOB Price:Get Latest Price

1 Kilogram

FOB Price:USD 35.0000 -49.0000
  • Min.Order :1 Kilogram
  • Purity: 99%
  • Payment Terms : T/T,Other

Keywords

Dihydroartemisinin 71939-50-9 DHQHS 2

Quick Details

  • Appearance:white powder
  • Application:Pharmaceutical;Food Preservative;Cosmetics;Food
  • PackAge:1kg/bag,5kg/bag,25kg/drum
  • ProductionCapacity:5000|Kilogram|Month
  • Storage:in a cool&dry place
  • Transportation:By air,By Sea

Superiority:

Dihydroartemisinin

CAS: 81496-81-3;71939-50-9;123930-80-3

Molecular Formula: C15H24O5

  1. Home
  2. Product Category
  3. other
  4. other
  5. 71939-50-9

71939-50-9 - Names and Identifiers

Name alpha-Dihydroartemisinin
Synonyms BDIH
dhqhs 1
DHQHS 1
Artenimol
artenimol
Artenimol [inn]
dihdyroartesiminin
Dihydroartemisinine
Di-hydro artemisinin
alpha-dihydroartemisinin
alpha-Dihydroartemisinin
DihydroarteMisinin (α,β Mixture)
(5aS,6R,9R,10S,12R,12aR)-3,6,9-trimethyldecahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-10-ol
(3R,5aS,6R,8aS,9R,12R,12aR)-3,6,9-trimethyldecahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-10-ol
(3R,5aS,6R,9R,10S,12R,12aR)-3,6,9-trimethyldecahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-10-ol
(5aS,6R,8aS,9R,10S,12R,12aR)-3,6,9-trimethyldecahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-10-ol
(3R,5aS,6R,8aS,9R,10S,12R,12aR)-3,6,9-trimethyldecahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-10-ol
(3R,5aS,6R,8aS,9R,10R,12R,12aR)-Decahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10-ol
CAS 81496-81-3
71939-50-9
123930-80-3
EINECS 617-239-7
InChI InChI=1/C15H24O5/c1-8-4-5-11-9(2)12(16)17-13-15(11)10(8)6-7-14(3,18-13)19-20-15/h8-13,16H,4-7H2,1-3H3/t8-,9-,10+,11+,12 ,13-,14-,15-/m1/s1

71939-50-9 - Physico-chemical Properties

Molecular Formula C15H24O5
Molar Mass 284.35
Density 1.24±0.1 g/cm3(Predicted)
Melting Point 142-144°C
Boling Point 375.6±42.0 °C(Predicted)
Specific Rotation(α) +129 (c, 0.92 in CHCl3)
Flash Point 181°C
Solubility Easily soluble in chloroform, dissolved in acetone, slightly soluble in methanol or ethanol, almost insoluble in water.
Vapor Presure 3.52E-07mmHg at 25°C
Appearance White needle crystal
Color White to Off-White
pKa 12.61±0.70(Predicted)
Storage Condition 2-8°C
Refractive Index 1.542
MDL MFCD00274495
Physical and Chemical Properties White needle Crystal, odorless, bitter taste. It is soluble in chloroform and soluble in acetone. Slightly soluble in methanol or ethanol, almost insoluble in water. The melting point was 145-150 °c.

71939-50-9 - Reference

Reference 

Show more

 1. Zhu Chunyan, Xu Qiong, Mao Zhiyun, etc. Comparison of effects of three artemisinin derivatives on pain co-emotion dis...

71939-50-9 - Reference Information

Use dihydroartemisinin can be used in a variety of malaria, especially for anti-chloroquine, treatment of falciparum malaria and dangerous cerebral malaria.
medicinal properties and application dihydroartemisinin has a strong killing effect on asexual bodies of Plasmodium falciparum, it can quickly control the symptoms and kill the various forms of the malaria parasite in the vegetative period, and it is also effective for chloroquine and piperaquine resistant falciparum malaria, and the toxicity is low. Animal experiments have found that administration in the induction phase of pregnancy in mice can increase the occurrence of fetal absorption, but no teratogenic effect. Oral absorption, oral administration of this product 2 mg/kg,tmax 1.33h,Cmax 0.71 μg/ml. Clinical for various types of malaria, especially for chloroquine, piperaquine-Resistant Brain, dangerous disease of falciparum malaria rescue.
adverse reactions There was a transient decrease in peripheral reticulocytes and white blood cells, and elevated transaminase. Dihydroartemisinin piperaquine has Nausea, Vomit, Abdominal Pain, Diarrhea and loss of appetite, etc., as well as dizziness, Head Pain, rash, skin itching and so on.
principle of action dihydroartemisinin is a derivative of artemisinin. Has a strong killing effect on the parasite asexual body, can quickly control the symptoms, and kill the protozoa, against chloroquine, Piva falciparum equally effective.
contraindication is contraindicated for those allergic to this product. Severe liver and kidney disease, blood diseases, the first 3 months of pregnancy disabled Dihydroartemisinin and Piperaquine Phosphate Tablets.
precautions should be used with caution during pregnancy; Dihydroartemisinin and Piperaquine Phosphate Tablets has a long half-life, and should not be used repeatedly within half a month.

 

  1. appropriate amounts of the product and the reference product of dihydroartemisinin were dissolved and diluted with toluene to prepare a solution containing about 0.1 mg per 1 ml, which was used as the test solution and the reference solution. According to the thin layer chromatography (General 0502) test, accurately absorb the above two solutions each 10 u1, point on the same silica gel G thin layer plate, with petroleum ether (boiling range is 40~60°C)-Ether (1:1) as a developing solvent, expand, dry, sprayed with 2% vanillin in sulfuric acid ethanol solution (20-100), heated at 85 ° C. For 10-20 minutes to clear spots. The position and color of the main spot displayed by the test solution should be consistent with the main spot of the control solution.
  2. in the chromatogram recorded under the content determination item, the retention time of the main peak of the test solution should be consistent with the retention time of the main peak of the reference solution.
  3. The infrared absorption spectrum of this product should be consistent with that of the control (Spectrum set 696).
  4. two items (1) and (2) above can be selected as one item.

 

Details:

DHQHS 2

Mol Download Chemical properties

CAS:

71939-50-9

MF:

C15H24O5

MW:

284.35

EINECS:

MDL No.:

MFCD18323866

Properties

Melting point:

144-149°C

Boiling point:

375.6±42.0 °C(Predicted)

Density 

1.24

storage temp. 

Inert atmosphere,2-8°C

solubility 

DMSO : 41.67 mg/mL (146.54 mM; Need ultrasonic)

pka

12.61±0.70(Predicted)

form 

solid

color 

White to Almost white

Merck 

14,817


Xi'an Eastling biotech Co., Ltd. is dedicated to the research and development, production, and sales of natural plant extracts; With nearly 15 years of experience in identifying, researching, developing, and producing active ingredients for medicinal plants, we focus on providing innovative products and services to customers in industries such as pharmaceuticals, health food, and cosmetics.

 

Eastling Biotechnology has established a global direct harvesting system for plant raw materials, ensuring the high quality and authenticity of raw materials, while also protecting the continuity and diversity of plants; Having strong research and development capabilities, we can develop more effective and specialized plant active ingredients for the pharmaceutical, health food, and cosmetics industries; We have established an advanced quality control system, and the quality control of our products depends on advanced testing instruments and high-level technical experts. The effective combination of the two forms Eastling's ability to quickly and rigorously control product quality.

 

We have a production system that complies with Chinese GMP and American cGMP certifications, as well as advanced and optimized large-scale industrial production technology. In addition to producing specific products for Eastling Biotechnology, we also provide customized services to meet the characteristics and needs of different customers to produce customized products.

We believe that natural active ingredients are the foundation of our service to customers. Scientific and effective production technology is the foundation for us to provide customers with specialized products. We have the ability to serve customers in the pharmaceutical, health food, and cosmetics industries, provide new product solutions, and add new value to their products.

View All
Visit Store

You Might Also Like

Related Searches

Contact Supplier

Confirm to collect the product to my collection?

OKCancel

About|Contact|Cas|Product Name|Molecular|Country|Encyclopedia

Message|New Cas|MSDS|Service|Advertisement|CAS DataBase|Article Data|Manufacturers | Chemical Catalog

©2008 LookChem.com,License: ICP

NO.:Zhejiang16009103

complaints:service@lookchem.com Desktop View