Top Quality Natural...

Top Quality Natural Baicalein
Top Quality Natural Baicalein

Top Quality Natural Baicalein

Min.Order / FOB Price:Get Latest Price

1 Kilogram

FOB Price:USD 35.0000 -49.0000

  • Min.Order :1 Kilogram
  • Purity: 99%
  • Payment Terms : T/T,Other

Keywords

Baicalein 491-67-8 Baicalein powder

Quick Details

  • Appearance:white powder
  • Application:Pharmaceutical;Food Preservative;Cosmetics;Food
  • PackAge:1kg/bag,5kg/bag,25kg/drum
  • ProductionCapacity:5000|Kilogram|Month
  • Storage:in a cool&dry place
  • Transportation:By air,By Sea

Superiority:

Baicalein

CAS: 491-67-8;27462-75-5

Molecular Formula: C15H10O5

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491-67-8 - Names and Identifiers

Name Baicalein
Synonyms Noroxylin
Baicalein
Baicelein
Baicaleine
5,6,7-Trihydroxyflavone
BAICALEIN(SH)NOW RG GRADE
5,6,7-trihydroxy-2-phenyl-4H-chromen-4-one
5,6,7-trihydroxy-2-phenyl-4H-chroMen-4-one
5,6,7-trihydroxy-2-phenyl-4-chromenone hydrate
5,6,7-trihydroxy-2-phenyl-4H-chromen-4-one hydrate
Baicalein, monohydrate, 5,6,7-Trihydroxy-2-phenyl-4H-chromen-4-one monohydrate
CAS 491-67-8
27462-75-5
EINECS 000-000-0
InChI InChI=1/C15H10O5.H2O/c16-9-6-11(8-4-2-1-3-5-8)20-12-7-10(17)14(18)15(19)13(9)12;/h1-7,17-19H;1H2
InChIKey FXNFHKRTJBSTCS-UHFFFAOYSA-N

491-67-8 - Physico-chemical Properties

Molecular Formula C15H10O5
Molar Mass 270.24
Density 1.3280 (rough estimate)
Melting Point 256-271 °C (lit.)
Boling Point 373.35°C (rough estimate)
Specific Rotation(α) -14°(water);-139°(pyridine)
Flash Point 347°C
Solubility Soluble in methanol, ethanol, acetone, ethyl acetate and hot glacial acetic acid, slightly soluble in chloroform, soluble in dilute sodium hydroxide is green brown, but unstable, easy to oxidize to green.
Vapor Presure 8.55E-18mmHg at 25°C
Appearance Yellow needle crystal (ethanol)
Color Yellow or yellow-green
Merck 14,942
BRN 272683
pKa 6.31±0.40(Predicted)
Storage Condition Keep in dark place,Sealed in dry,2-8°C
Stability Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 week.
Sensitive Sensitive to light and heat
Refractive Index 1.5000 (estimate)
MDL MFCD00017459
Physical and Chemical Properties Yellow prismatic crystals (from ethanol). Melting point 264~265 °c (decomposition). Soluble in ethanol, methanol, ether, acetone, ethyl acetate, hot glacial acetic acid, slightly soluble in chloroform and nitrobenzene, almost insoluble in water, soluble in dilute sodium hydroxide green Brown, concentrated sulfuric acid yellow and green fluorescence. It can also be synthesized chemically in the root of Scutellaria baicalensis Georgi, and in the seed and stem bark of the echinaceae plant xylem indicum (L.)Vent.
Use With anti-inflammatory, anti-allergic, diuretic, choleretic, cholesterol-lowering, anti-thrombosis, relieve asthma and other effects. It is also a specific inhibitor of mammalian liver salivary enzymes and has a role in the regulation of certain diseases. Industrial raw materials for the preparation of baicalin original phosphate for allergy, asthmatic Pneumonia, also as astringent, hemostatic.

 

491-67-8 - Reference Information

pharmacological activity baicalein, also known as baicalin yuan, is an important pharmacodynamic active ingredient in traditional Chinese medicine scutellaria baicalensis (ScutellariabaicalensisGeorge) and wood butterfly (Oroxylumindicum), with significant antioxidant, anti-inflammatory, anti-allergic, antibacterial, antiviral, anti-tumor and other pharmacological activities.
Biological activity Baicalein are CYP2C9 and prolyl endopeptidase inhibitors.
Target Value
Uses A flavonoid compound that is a xanthine oxidase inhibitor.
It has anti-inflammatory, anti-allergic, diuretic, choleretic, cholesterol-lowering, anti-thrombosis, and asthma relief. It is also a specific inhibitor of salivary enzymes in mammalian liver, which has the effect of regulating certain diseases. In industry, baicalin protophosphate is prepared from it as a raw material for allergies and asthmatic pneumonia, as well as astringents and hemostatic drugs.
production method 1. extract scutellaria baicalensis root, pulverize and boil with water for 3 times, combine the extracts, add acid to adjust the ph value to 4 after filtration, stir with slight heat, stand still, centrifuge to separate the precipitate. The sediment is washed with water with a ph of 4 and dried to produce crude products. The crude product is refluxed and hydrolyzed in 1.2 mol · L-1 hydrochloric acid with boiling water for several hours, and the precipitated product is scutellarin by cooling and filtering.

 

Details:

Baicalein

 

CAS:

491-67-8

MF:

C15H10O5

MW:

270.24

EINECS:

000-000-0

MDL No.:

MFCD00017459

Properties

Melting point:

256-271 °C (lit.)

Boiling point:

373.35°C (rough estimate)

Density 

1.3280 (rough estimate)

refractive index 

1.5000 (estimate)

storage temp. 

Keep in dark place,Sealed in dry,2-8°C

solubility 

DMSO (Slightly), Methanol (Slightly)

pka

6.31±0.40(Predicted)

form 

Yellow solid

color 

Yellow or yellow-green

Merck 

14,942

BRN 

272683

Stability:

Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 week.

InChIKey

FXNFHKRTJBSTCS-UHFFFAOYSA-N

LogP

3.310 (est)

Xi'an Eastling biotech Co., Ltd. is dedicated to the research and development, production, and sales of natural plant extracts; With nearly 15 years of experience in identifying, researching, developing, and producing active ingredients for medicinal plants, we focus on providing innovative products and services to customers in industries such as pharmaceuticals, health food, and cosmetics.

 

Eastling Biotechnology has established a global direct harvesting system for plant raw materials, ensuring the high quality and authenticity of raw materials, while also protecting the continuity and diversity of plants; Having strong research and development capabilities, we can develop more effective and specialized plant active ingredients for the pharmaceutical, health food, and cosmetics industries; We have established an advanced quality control system, and the quality control of our products depends on advanced testing instruments and high-level technical experts. The effective combination of the two forms Eastling's ability to quickly and rigorously control product quality.

 

We have a production system that complies with Chinese GMP and American cGMP certifications, as well as advanced and optimized large-scale industrial production technology. In addition to producing specific products for Eastling Biotechnology, we also provide customized services to meet the characteristics and needs of different customers to produce customized products.

We believe that natural active ingredients are the foundation of our service to customers. Scientific and effective production technology is the foundation for us to provide customers with specialized products. We have the ability to serve customers in the pharmaceutical, health food, and cosmetics industries, provide new product solutions, and add new value to their products.

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