Top Quality Natural...

Top Quality Natural Yohimbine hydrochloride
Top Quality Natural Yohimbine hydrochloride
Top Quality Natural Yohimbine hydrochloride

Top Quality Natural Yohimbine hydrochloride

Min.Order / FOB Price:Get Latest Price

1 Kilogram

FOB Price:USD 35.0000 -49.0000

  • Min.Order :1 Kilogram
  • Purity: 99%
  • Payment Terms : T/T,Other

Keywords

Yohimbine hydrochloride 65-19-0 Yohimbine

Quick Details

  • Appearance:white powder
  • Application:Pharmaceutical;Food Preservative;Cosmetics;Food
  • PackAge:1kg/bag,5kg/bag,25kg/drum
  • ProductionCapacity:5000|Kilogram|Month
  • Storage:in a cool&dry place
  • Transportation:By air,By Sea

Superiority:

65-19-0 - Physico-chemical Properties

Molecular Formula C21H27ClN2O3
Molar Mass 390.9
Melting Point 288-290°C (dec.)(lit.)
Boling Point 542.979°C at 760 mmHg
Specific Rotation(α) 99 º (c=1%, H2O, dry subst)
Flash Point 282.184°C
Solubility Easily soluble in chloroform, soluble in methanol and ethanol, slightly soluble in water.
Vapor Presure 0mmHg at 25°C
Appearance White fine powder
Color white to off-white
Merck 14,10102
Storage Condition Keep in dark place,Inert atmosphere,Room temperature
Sensitive Light Sensitive
Refractive Index 103 ° (C=1, H2O)
MDL MFCD00012674
In vitro study Yohimbine(Antagonil) is used as a mydriatic and also in the treatment of impotence. It is also considered to be a drug. Yohimbine is a presynaptic Alpha 2 adrenergic blocker. Yohimbine exerts a beneficial effect on erectile function by blocking central α2 Adrenergic receptors, acting on parasympathetic nerves to increase the release of norepinephrine and the rate of excitation of cells in the noradrenergic nuclei of the brain.
In vivo study LD50: Mouse 55 mg/kg (I. p.)

 

properties white crystalline powder with slightly bitter taste.
Use Clinical single dose for the treatment of various types of male impotence and sexual dysfunction.
An alpha -2 adrenergic receptor inhibitor that blocks pre-or post-synaptic alpha -2 adrenergic receptors, causing the release of norepinephrine and dopamine.
Overview Yohimbine hydrochloride (C21H26N2O3HCL), also known as Yohimbine hydrate, Yohimbine hydrochloride, comfort ledes tablets, comfort ledes, appearance is white to milky white fine powder, gas fragrance, bitter slightly astringent, melting point 288 ℃ ~ 290 ℃, soluble in chloroform, soluble in methanol, ethanol, slightly soluble in water. Plant source dried bark of the wild African plant Yohimbe or extracts of the bark of the West African plant kenanum of the Rubiaceae family. Pharmacological effects of increased muscle tension, urine inhibition without damage; Accelerate the body energy metabolism, increase energy supply. Clinical single agent for the treatment of male impotence and sexual dysfunction. The mechanism of action is to selectively block the presynaptic α2 receptor, promote the release of norepinephrine, so that the cavernous nerve endings release more norepinephrine, reduce the venous return of the penis, and facilitate the congestion and erection, and can increase the secretion of sexual fluid. A small amount of application, can make the perineum swelling, stimulate the spinal cord erection Center and the sexual function.
principle of action can selectively block presynaptic α2 receptors and promote the release of norepinephrine, the cavernous nerve endings release more norepinephrine, reduce penile venous reflux, conducive to congestion erection, and can increase the secretion of sexual fluid. A small amount of application, can make the perineum swelling, stimulate the spinal cord erection Center and the sexual function.
biological activity Yohimbine (Antagonil) is a pupillary dilator used to treat impotence and is an aphrodisiac.
Target Value

 

Details:

Yohimbine hydrochloride

CAS:

65-19-0

MF:

C21H27ClN2O3

MW:

390.9

EINECS:

200-600-4

MDL No.:

MFCD00012674

Properties

Melting point:

288-290 °C (dec.)(lit.)

alpha 

99 º (c=1%, H2O, dry subst)

refractive index 

103 ° (C=1, H2O)

storage temp. 

Keep in dark place,Inert atmosphere,Room temperature

solubility 

H2O: 10 mg/mL

form 

powder

color 

white to off-white

optical activity

[α]/D 100±5°, c = 1 in H2O

Sensitive 

Light Sensitive

Merck 

14,10102

InChIKey

PIPZGJSEDRMUAW-VJDCAHTMSA-N

SMILES

N1C2=C(C=CC=C2)C2=C1[C@@]1(C[C@]3([C@](CC[C@@H]([C@@H]3C(OC)=O)O)([H])CN1CC2)[H])[H].[H]Cl |&1:9,11,12,15,16,r|

LogP

2.201 (est)

Xi'an Eastling biotech Co., Ltd. is dedicated to the research and development, production, and sales of natural plant extracts; With nearly 15 years of experience in identifying, researching, developing, and producing active ingredients for medicinal plants, we focus on providing innovative products and services to customers in industries such as pharmaceuticals, health food, and cosmetics.

 

Eastling Biotechnology has established a global direct harvesting system for plant raw materials, ensuring the high quality and authenticity of raw materials, while also protecting the continuity and diversity of plants; Having strong research and development capabilities, we can develop more effective and specialized plant active ingredients for the pharmaceutical, health food, and cosmetics industries; We have established an advanced quality control system, and the quality control of our products depends on advanced testing instruments and high-level technical experts. The effective combination of the two forms Eastling's ability to quickly and rigorously control product quality.

 

We have a production system that complies with Chinese GMP and American cGMP certifications, as well as advanced and optimized large-scale industrial production technology. In addition to producing specific products for Eastling Biotechnology, we also provide customized services to meet the characteristics and needs of different customers to produce customized products.

We believe that natural active ingredients are the foundation of our service to customers. Scientific and effective production technology is the foundation for us to provide customers with specialized products. We have the ability to serve customers in the pharmaceutical, health food, and cosmetics industries, provide new product solutions, and add new value to their products.

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