Top Quality Natural...

Top Quality Natural Fisetin
Top Quality Natural Fisetin
Top Quality Natural Fisetin

Top Quality Natural Fisetin

Min.Order / FOB Price:Get Latest Price

1 Kilogram

FOB Price:USD 35.0000 -49.0000
  • Min.Order :1 Kilogram
  • Purity: 99%
  • Payment Terms : T/T,Other

Keywords

Fisetin 528-48-3 Fisetin powder

Quick Details

  • Appearance:Yellow powder
  • Application:Pharmaceutical;Food Preservative;Cosmetics;Food
  • PackAge:1kg/bag,5kg/bag,25kg/drum
  • ProductionCapacity:5000|Kilogram|Month
  • Storage:in a cool&dry place
  • Transportation:By air,By Sea

Superiority:

528-48-3 - Physico-chemical Properties

Molecular Formula C15H10O6
Molar Mass 286.24
Density 1.2981 (rough estimate)
Melting Point >330°C(lit.)
Boling Point 348.61°C (rough estimate)
Flash Point 233°C
Solubility Soluble in ethanol, acetone and acetic acid. Almost insoluble in water, ether, benzene, chloroform and petroleum ether.
Vapor Presure 3.23E-15mmHg at 25°C
Appearance Yellow needle crystal (dilute ethanol)
Color Pale Yellow to Very Dark Yellow
Merck 14,4088
BRN 292829
pKa 6.83±0.40(Predicted)
Storage Condition Sealed in dry,Store in freezer, under -20°C
Stability Hygroscopic
Refractive Index 1.4413 (estimate)
MDL MFCD00006829
Physical and Chemical Properties Soluble in ethanol, acetone and acetic acid. Almost insoluble in water, ether, benzene, chloroform and petroleum ether. It is derived from the plants such as wood and tree Rhus suce Danea L Wood

 

overview luffin (Fisetin) is a polymer pharmaceutical raw material. This product is a yellow needle-like crystal, derived from the lacquer family plants, wax tree RhussuccedaneaL, coggygria, etc. Soluble in ethanol, acetone and acetic acid. Almost insoluble in water, ether, benzene, chloroform and petroleum ether. It has an inhibitory effect on the production of prostate cord in 3T3 mice fibroblasts with methylcholanthracene transmutation, and the half effective inhibitory concentration (ID50) is 42.0UM. It has inhibitory effect on the whole sugar reductase of rat eye lens, and the half effective inhibitory concentration is 10-6M; for mouse small intestine specimens, its anti-acetylcholine spasmodic effect is the 166% of papaverine. A team of Japanese and American researchers found through animal experiments that the lutein in vegetables and fruits can help improve memory.
detection method HPLC ≥ 98%
specifications 10 mg20mg100mg500mg1g (can be packaged according to customer requirements)
traits this product is yellow needle crystal
function and use this product is used for content determination.
extraction source this product is extract of sumac plant


fig. 1 one of the sources of envery flavin-coggygria extract
physical properties yellow needle crystal (dilute ethanol), melting point 330 ℃ (decomposition). Soluble in ethanol, acetone

and acetic acid. Almost insoluble in water, ether, benzene, chloroform and petroleum ether. Melting point 348 ℃, bright yellow fine needle crystal

, melting point> 300 ℃
pharmacological action 1. inhibition of prostaglandin: inhibitory effect on the formation of prostatic cord in 3T3 mouse fibroblasts transformed from methylcholanthracene, with a half effective inhibitory concentration (ID50) of 42.0UM.
2. Enzyme inhibition: it has inhibitory effect on the whole sugar reductase of rat eye lens, and the half effective inhibitory concentration is 10-6M
3. antispasmodic: on mouse small intestine specimens, its antiacetylcholine spasmodic effect is the 166% of papaverine.
4. A team composed of Japanese and American researchers found through animal experiments that the lutein in vegetables and fruits can help improve memory.
extraction rate experiment 20g of yellow protection was weighed, totaling 5 batches. Under the optimal extraction process, reflux extraction until the extract is nearly colorless, combine the extract, filter and concentrate, move to a 1000ml volumetric flask, add ethanol to the scale, and shake well.
accurately absorb 1ml and place it in a 100ml volumetric flask, add ethanol to dilute to scale, shake well, measure its absorbance at 367±1nm wavelength of ultraviolet spectrophotometer according to the determination method of envery flavin content in yellow pond pulp, calculate the content and extraction rate of envery flavin in the sample according to the 847.52 of C12H10O6 absorption coefficient, and see table 1 for the results.


table 1 extraction rate of luffin in coggygria coggygria
references [1] lutein. Bailian database.[2017/08.20]
[2] Fisetin.[2017/08.20]
[3] Tang Jianhua, Shen Qingliang. Study on extraction rate of luffin from Cotinus coggygria [J]. Chinese patent medicine, 1992,(08):10.
use used for content determination/identification/pharmacological experiments, etc. Pharmacological effects: 1. Inhibition of prostaglandins: It has an inhibitory effect on the formation of the prostate cord of 3T3 mice fibroblasts mutated by methylcholanthracene, and the half effective inhibitory concentration (ID50) is 42.0UM. 2. Enzyme inhibition: It has inhibitory effect on the whole sugar reductase of rat eye lens, and the half effective inhibitory concentration is 10-6M. 3. Antispasmodic: For small intestine specimens of mice, its antispasmodic effect against acetylcholine is the 166% of papaverine. 4. A team of Japanese and American researchers found through animal experiments that the lutein in vegetables and fruits can help improve memory.
a naturally occurring flavonol with therapeutic activity, used to synthesize anti-inflammatory, anticonvulsant and antiproliferative drugs with pharmaceutical activity.

 

Details:

Fisetin

CAS:

528-48-3

MF:

C15H10O6

MW:

286.24

EINECS:

208-434-4

MDL No.:

MFCD00006829

Properties

Melting point:

>330 °C(lit.)

Boiling point:

348.61°C (rough estimate)

Density 

1.2981 (rough estimate)

refractive index 

1.4413 (estimate)

storage temp. 

Sealed in dry,Store in freezer, under -20°C

solubility 

DMSO (Slightly), Methanol (Slightly)

pka

6.83±0.40(Predicted)

form 

Solid

Colour Index 

75620

color 

Pale Yellow to Very Dark Yellow

Merck 

14,4088

BRN 

292829

Stability:

Hygroscopic

InChI

InChI=1S/C15H10O6/c16-8-2-3-9-12(6-8)21-15(14(20)13(9)19)7-1-4-10(17)11(18)5-7/h1-6,16-18,20H

InChIKey

XHEFDIBZLJXQHF-UHFFFAOYSA-N

SMILES

C1(C2=CC=C(O)C(O)=C2)OC2=CC(O)=CC=C2C(=O)C=1O

LogP

1.970 (est)

Xi'an Eastling biotech Co., Ltd. is dedicated to the research and development, production, and sales of natural plant extracts; With nearly 15 years of experience in identifying, researching, developing, and producing active ingredients for medicinal plants, we focus on providing innovative products and services to customers in industries such as pharmaceuticals, health food, and cosmetics.

 

Eastling Biotechnology has established a global direct harvesting system for plant raw materials, ensuring the high quality and authenticity of raw materials, while also protecting the continuity and diversity of plants; Having strong research and development capabilities, we can develop more effective and specialized plant active ingredients for the pharmaceutical, health food, and cosmetics industries; We have established an advanced quality control system, and the quality control of our products depends on advanced testing instruments and high-level technical experts. The effective combination of the two forms Eastling's ability to quickly and rigorously control product quality.

 

We have a production system that complies with Chinese GMP and American cGMP certifications, as well as advanced and optimized large-scale industrial production technology. In addition to producing specific products for Eastling Biotechnology, we also provide customized services to meet the characteristics and needs of different customers to produce customized products.

We believe that natural active ingredients are the foundation of our service to customers. Scientific and effective production technology is the foundation for us to provide customers with specialized products. We have the ability to serve customers in the pharmaceutical, health food, and cosmetics industries, provide new product solutions, and add new value to their products.

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