Eastling Supply 16-Dehydropregnenolone acetate Powder

Details:

Product Description:

16-Dehydropregnenolone acetate (16-DPA) is a C21 steroid hormone that is naturally produced in the human body, and is an important intermediate in the biosynthesis of other steroid hormones. It is a key intermediate in the synthesis of progesterone, androgens, estrogens, and glucocorticoids. 16-DPA is also known as pregnenolone acetate, and is a synthetic form of pregnenolone, a precursor for the production of steroid hormones. 16-DPA has been studied extensively for its potential medical applications, and is currently being investigated for its potential use in the treatment of various diseases.

16-DPA - Names and Identifiers: 

Name	16-dehydropregnenolone acetate
Synonyms	16-DPA 16 DPA 16-dehydropregnenolone acetate 3b-Acetoxy-5,16-pregnadien-20-one 5,16-Pregnadien-3-ol-20-one acetate 5,16-Pregnadien-3b-ol-20-one acetate 4-Toluenesulfonic Acid Monohydrate 16-DEHYDROPREGNENOLONE ACETATE (16-DPA) 20-oxopregna-5,16-dien-3-beta-yl acetate 3b-Hydroxy-5,16-pregnadien-20-one acetate (3beta)-20-oxopregna-5,16-dien-3-yl acetate
CAS	979-02-2
EINECS	213-558-7
InChI	InChI=1/C23H32O3/c1-14(24)19-7-8-20-18-6-5-16-13-17(26-15(2)25)9-11-22(16,3)21(18)10-12-23(19,20)4/h5,7,17-18,20-21H,6,8-13H2,1-4H3/t17-,18-,20-,21-,22-,23+/m0/s1
InChIKey	MZWRIOUCMXPLKV-RFOVXIPZSA-N

16-DPA - Physico-chemical Properties: 

Molecular Formula	C23H32O3
Molar Mass	356.50
Density	1.11g/cm3
Melting Point	170-178℃
Boling Point	464.4°C at 760 mmHg
Flash Point	200.1°C
Vapor Presure	8.38E-09mmHg at 25°C
Storage Condition	Room Temprature
Refractive Index	1.546
Physical and Chemical Properties	Chemical properties White crystalline powder, no odor, no odor, stable in the air, soluble in ethanol, methanol, insoluble in water.
Use	It can be used as a steroid hormone drug intermediate, and can be used to manufacture corticosteroids, protein curing hormones, male hormones, and luteinizing hormones.

Specifications: 

roduct Name	16-Dehydropregnenolone Acetate
Specification	According with Enterprise Standard
Items	Standard	Results
Appearance	White or almost white crystalline powder,odorless	Complies
Color	No deeper than standard liquid color	Complies
Loss on Drying	≤0.5%	0.20%
Melting Point	165℃~175℃	165℃-173℃
Assay	≥98.5%	99.03%
Conclusion	The items tested conform to the requirements of enterprise standard.

Biochem/physiol Actions: 

16-Dehydropregnenolone acetate (16-DPA) is synthesized from steroids sapogenin, diosgenin and solasodine. 16-Dehydropregnenolone acetate (16-DPA) is a crucial intermediate for the synthesis of steroid hormones-based drugs. It is an antagonist for farnesoid X receptor (FXR) and modulates cholesterol metabolism. It is considered as a potential antihyperlipidemic agent. Chemically synthesized steroid derivatives from DPA have cytotoxic features and could serve as potential anticancer agents.

Future Directions: 

Future research into 16-DPA could focus on its potential use in the treatment of various diseases, such as Alzheimer’s disease, cancer, and other neurological disorders. Additionally, further research could focus on its potential role in the regulation of energy metabolism, and its ability to improve insulin sensitivity. Additionally, further research could also focus on its potential use in the development of novel drugs and therapies.

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