(S)-12-hydroxy-1,10-bis(2,4,6-triisopropylphenyl)-4,5,6,7-tetrahydrodiindeno[7,1-de:1',7'-fg][1,3,2]dioxaphosphocine 12-oxide

Superiority:

At present, the company has a 1,000-square-meter organic synthesis laboratory, and the R&D team includes a number of doctors and masters, as well as several bachelors operators. It has world-renowned brands of advanced analytical equipment and professional analytical method development team (Agilent HPLC, GC, UPLC, LC-MS, GC-MS, UV, Metrohm titrator and automatic potentiometric titrator, TA DSC, Thermo CAD detector, etc.). The company has strong R&D technical capabilities, and can better solve the synthesis route research and development, process scale-up, and difficult analysis and testing problems of complex compounds for customers. At the same time, the company is involved in the sales and maintenance of instruments and equipment related to biology and chemistry, and can provide customers with complete services from process research and development to production-level equipment construction.

The main products are applied to the linker part of new ADC drugs, and all technologies come from the independent research and development and innovation of the company's R&D team. The main advantageous products are several key materials used in ADC drug linkers - polyethylene glycol compounds, monodisperse polyethylene glycol derivatives (amino groups, carboxylic acids, azides), etc. Flow skids are used to completely solves the risk of explosion in the synthesis process of this compound, and also increase the production capacity. Synthesis of Azide compounds at the 100 kg scale was achieved by optimizing the continuous flow reaction process. The purity of its products has reached 99%+, and the key impurities (homologues and derivatives) are controlled at a high-quality level of less than 0.3%.