- Min.Order :10 Gram
- Purity: 98
- Payment Terms : T/T,
Keywords
Avanafil 99% high purity
Quick Details
- Appearance:powder
- Application:Chemical,pharmaceutical intermediates
- PackAge:Aluminum foil bag
- ProductionCapacity:100|Kilogram|Day
- Storage:Seal and store away from light
- Transportation: by courier，by air or by sea.
Superiority:
Hubei Langyou International Trading Co., Ltd is a renowned pharmaceutical manufacturer. We specializing in the production of research and development of pharmaceutical intermediates, this kind of products with high quality price concessions, welcomed the new and old customers advisory purchase, companies invest large fund and brain research fine chemical r&d department,biochemical, pharmaceutical and intermediate products to meet the demand of the market. High level research team,advanced equipment and good scientific atmosphere ensure the quality .
1.Reasonable and competitive price. Provide the best and professional service.Provide the best and professional service is our purpose.
2. Reliable shipping way.Door to door service, guarantee 100% delivery for you.
We have our own shipping agent in each country,we have special lines to your country, you no need do anything.
Will finish all the customs clearance at our side, customers are without any customs issues,door to door delivery.
3.To below countries, we are very familiar and regular.
UK,USA,Canada,Russia,Ukraine,Kazakhstan,Belarus,Germany,Poland,Sweden,the Netherlands, Australia,Spain,Mexico,Poland and so on. All are without problems.
Details:
Product Name: Avanafil
CAS: 330784-47-9
MF: C23H26ClN7O3
MW: 483.95
Melting point 150-152°C
density 1.372
storage temp. Sealed in dry,Store in freezer, under -20°C
solubility DMSO (Slightly), Methanol (Slightly, Heated)
pka 11.84±0.46(Predicted)
form Solid
color White to Off-White
Avanafil (Zepeed) was approved by the Korean Health Ministry for the treatment of erectile dysfunction (ED) in August 2011. Avanafil is a highly selective type 5 phosphodiesterase (PDE5) inhibitor. Avanafil is reported to be the most selective PDE5 inhibitor on the market. The onset of Tmax and half-life also varies among the marketed PDE5 inhibitors. Sildenafil has a Tmax at 1 h and a half-life of 3–5 h. Vardenafil is somewhat similar with a Tmax of 0.6 h and a half-life of 4–6 h. Tadalafil has the longest half-life among the marketed drugs with a half-life of 17 h. Avanafil has a fast onset of action reaching Tmax in 0.6 h with a half-life of 1.2 h. A synthesis of avanafil (TA-1790) is described in the patent literature. The main elimination route of avanafil is through the bile and feces. Avanafil was also found to be reabsorbed through enterohepatic recirculation.
Chemical Properties White Solid
Uses Avanafil is a highly selective PDE5 inhibitor with IC50 of 1 nM.
Uses A phosphodiesterase (PDE5) inhibitor, used to treat erectile dysfunction.
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