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GLYX 13 117928-94-6 98%
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GLYX13
英文同义词L-ThreoninaMide,L-threonyl-L-prolyl-L-prolyl-;GLYX-13trifluoroacetate;L-Threonyl-L-prolyl-L-prolyl-L-threoninamidetrifluorChemicalbookoacetate;GLYX13;Thr-Pro-Pro-Thr-NH2trifluoroacetate;TPPT-amidetrifluoroacetate;Rapastinel;GIYX-13
CAS号117928-94-6
分子式C18H31N5O6
分子量413.47
沸点844.2±65.0°C(Predicted)
密度1.370±0.06g/cm3(Predicted)储存条件Keepindarkplace,Inertatmosphere,Storeinfreezer,under-20°C
溶解度DMChemicalbookF：25mg/mL；
DMSO：15mg/mL；
乙醇：10mg/mL；
PBS（pH7.2）：5mg/mL
形态粉末
酸度系数(pKa)12.26±0.45(Predicted)
颜色白色至棕褐色水溶解性Solubleto2mg/mlinwater
Rapatinib is an NMDAR(N-methyl-D-aspartate receptor) modulator with partial agonist properties. Rapastinel is a new antidepressant drug approved as an adjunct treatment for treatment-resistant major depressive disorder. It is a centrally active, intravenously administered (non-oral) Chemicalbook amideated tetrapeptide that acts as a selective, weak local agonist (mixed antagonist/agonist) at the glycine site of the NMDA receptor complex (Emax25%). The drug is a fast, long-acting antidepressant with the ability to inhibit and enhance NMDA receptor-mediated signal transduction, and is a powerful intellectual enhancer.
Details:
Rapatinib is an NMDAR(N-methyl-D-aspartate receptor) modulator with partial agonist properties. Rapastinel is a new antidepressant drug approved as an adjunct treatment for treatment-resistant major depressive disorder. It is a centrally active, intravenously administered (non-oral) Chemicalbook amideated tetrapeptide that acts as a selective, weak local agonist (mixed antagonist/agonist) at the glycine site of the NMDA receptor complex (Emax25%). The drug is a fast, long-acting antidepressant with the ability to inhibit and enhance NMDA receptor-mediated signal transduction, and is a powerful intellectual enhancer.
GLYX13
英文同义词L-ThreoninaMide,L-threonyl-L-prolyl-L-prolyl-;GLYX-13trifluoroacetate;L-Threonyl-L-prolyl-L-prolyl-L-threoninamidetrifluorChemicalbookoacetate;GLYX13;Thr-Pro-Pro-Thr-NH2trifluoroacetate;TPPT-amidetrifluoroacetate;Rapastinel;GIYX-13
CAS号117928-94-6
分子式C18H31N5O6
分子量413.47
沸点844.2±65.0°C(Predicted)
密度1.370±0.06g/cm3(Predicted)储存条件Keepindarkplace,Inertatmosphere,Storeinfreezer,under-20°C
溶解度DMChemicalbookF：25mg/mL；
DMSO：15mg/mL；
乙醇：10mg/mL；
PBS（pH7.2）：5mg/mL
形态粉末
酸度系数(pKa)12.26±0.45(Predicted)
颜色白色至棕褐色水溶解性Solubleto2mg/mlinwater
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