Seractide 12279-41-3 98%
MSDS Information |
Provider | Language |
---|---|
SigmaAldrich | English |
Seractide Usage And Synthesis |
Uses | Hormone (adrenocorticotropic). |
Brand name | Acthar Gel-Synthetic (Armour). |
General Description | Adrenocorticotropic hormone (ACTH) is a 303-amino acid hormone protein, which is located at human chromosome 2p23.3. |
Biochem/physiol Actions | Adrenocorticotropic hormone (ACTH) stimulates melanocortin receptor (MC1R to MC5R).It is implicated in the production of α-melanocyte-stimulating hormone (α-MSH). Hypomethylation of ACTH promoter region in thymic carcinoids is associated with ectopic adrenocorticotropic hormone syndrome. Mutations in this gene are associated with aberrant fusion protein and impairing melanocortin signaling in hypoadrenalism. Dysregulation of ACTH leads to Cushing disease. |
storage | Store at -20°C |
MSDS Information |
Provider | Language |
---|---|
SigmaAldrich | English |
Seractide Usage And Synthesis |
Uses | Hormone (adrenocorticotropic). |
Brand name | Acthar Gel-Synthetic (Armour). |
General Description | Adrenocorticotropic hormone (ACTH) is a 303-amino acid hormone protein, which is located at human chromosome 2p23.3. |
Biochem/physiol Actions | Adrenocorticotropic hormone (ACTH) stimulates melanocortin receptor (MC1R to MC5R).It is implicated in the production of α-melanocyte-stimulating hormone (α-MSH). Hypomethylation of ACTH promoter region in thymic carcinoids is associated with ectopic adrenocorticotropic hormone syndrome. Mutations in this gene are associated with aberrant fusion protein and impairing melanocortin signaling in hypoadrenalism. Dysregulation of ACTH leads to Cushing disease. |
storage | Store at -20°C |
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