Lysipressin

Details:

Lypressin Chemical Properties
Boiling point     1610.4±65.0 °C(Predicted)
density     1.1080 (rough estimate)
refractive index     1.6700 (estimate)
storage temp.     -20°C
pka    9.90±0.15(Predicted)
form     Solid
Sequence    H-[Cys-Tyr-Phe-Gln-Asn-Cys]-Pro-Lys-Gly-NH2，(Disulfide bridge: Cys-Cys)
InChIKey    NKWAIKZITYLOMT-DHSVNZEYSA-N
SMILES    C1(N)CSSCC(C(=O)N2C(C(=O)CC(CCCCN)C(=O)NCC(=O)N)CCC2)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(CC2=CC=CC=C2)NC(=O)C(CC2C=CC(O)=CC=2)NC1=O)CCC(=O)N
Safety Information
Hazard Codes     Xn
Risk Statements     20
Safety Statements     36
WGK Germany     3
RTECS     YW8659000
HS Code     2937190000
MSDS Information
Lypressin Usage And Synthesis
Uses    Hormone (antidiuretic).
Uses    Lypressin is a neurohypophysial hormone that regulates water, glucose, and salts in blood.
Definition    ChEBI: (2S)-N-[(2S)-6-amino-1-[(2-amino-2-oxoethyl)amino]-1-oxohexan-2-yl]-1-[[(4R,7S,10S,13S,16S,19R)-19-amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-13-(phenylmethyl)-1,2-dithia-5,8,11,14,17-pentazacycloeicos-4-yl]-oxomethyl]-2-pyrrolidinecarboxamide is a cyclic peptide.
Brand name    Pitressin (Parke-Davis).
General Description    Lypressin is synthetic 8-L-lysine vasopressin,a polypeptide similar to ADH. The lysine analog isconsidered more stable, and it is absorbed rapidly from thenasal mucosa. Lypressin (Diapid) is pharmaceutically availableas a topical solution, spray, 50 pressor units(185 g)/mL in 5-mL containers. Usual dosage, topical (intranasal),one or more sprays applied to one or both nostrilsone or more times daily.