1778-02-5 Pregnenolone Pregnenolone acetate
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Product introduction:
pregnenolone is a steroid hormone involved in the steroidogenesis of progesterone, mineralocorticoids, glucocorticoids, androgens, and estrogens. as such it is a prohormone. pregnenolone is a gabaa antagonist and increases neurogenesis in the hippocampus.like other steroids, pregnenolone consists of four interconnected cyclic hydrocarbons. it contains ketone and hydroxyl functional groups, two methylbranches, and a double bond at c5, in the b cyclic hydrocarbon ring. like all steroid hormones, it is hydrophobic. its esterified version, pregnenolone sulfate, is water-soluble.
Specifications :
items | standard | results |
characteristics | white or almost white crystalline powder | almost white crystalline powder |
melting point | 152~156 | 155.0~155.5 |
specific optical rotation | -16° -19° | -17.4° |
identification | the retention time of the major peak in the chromatogram of the assay preparation corresponds to that in the chromatogram of the standard preparation, as obtained in the assay | conforms |
uv absorption max. at 266 nm | conforms | |
ir spectra is consistent with crs | conforms | |
ph | 4.5~6.5 | 5.2 |
chlorides | ≤ 0.02% | 0.02% |
fluorides | ≥ 4.8% | 4.80% |
related substances | individual impurity ≤ 0.5% | 0.50% |
total impurities ≤ 2.0% | 0.90% | |
residue on ignition | ≤ 0.1% | 0.07% |
water | ≤ 0.5% | 0.06% |
heavy metals | ≤ 20ppm |
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