L-SEPIAPTERIN

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25 Milligram	Negotiable

25 Milligram

Negotiable

Min.Order :25 Milligram
Purity: 98
Payment Terms : T/T

Keywords

L-SEPIAPTERIN CAS 17094-01-8 98

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Appearance:WHITE SOLID
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ProductionCapacity:1000|Gram|
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L-SEPIAPTERIN Basic information
Product Name:   L-SEPIAPTERIN
Synonyms:   (S)-2-aMino-6-(2-hydroxypropanoyl)-7,8-dihydropteridin-4(1H)-one;(S)-2-AMino-6-(2-hydroxypropanoyl)-7,8-dihydropteridin-4(3H)-one;Sepiapterin solid;S(-)-2-AMINO-7,8-DIHYDRO-6-(2-HYDROXY-1-OXOPROPYL)-4(1H)-PTERIDINONE;SEPIAPTERIN;L-SEPIAPTERIN;L-SEPIAPTERIN DIHYDRATE;2-AMINO-7,8-DIHYDRO-6-(2S-HYDROXY-1-OXOPROPYL)-4(1H)-PTERIDINONE
CAS:   17094-01-8
MF:   C9H11N5O3
MW:   237.22
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Mol File:   17094-01-8.mol

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L-SEPIAPTERIN Chemical Properties
Melting point    >270 °C (dec.)
Boiling point    448.1±55.0 °C(Predicted)
density    1.86±0.1 g/cm3(Predicted)
storage temp.    -20°C
solubility    DMSO: 27 mg/mL
pka   12.33±0.20(Predicted)
form    solid
color    yellow
Stability:   Light Sensitive
CAS DataBase Reference   17094-01-8
Safety Information
Safety Statements    24/25
WGK Germany    3
MSDS Information
Provider   Language
ACROS   English
SigmaAldrich   English
L-SEPIAPTERIN Usage And Synthesis
Chemical Properties   yellow to orange powder
Uses   L-Sepiapterin serves as a substrate for BH4 synthesis via the pterin salvage pathway. It inhibits rat liver GTP cyclohydrolase with an IC50 value of approximately 25 μM. It can be used to circumvent the inhibition of pterin biosynthesis by 2,4-diamino-6-hydroxy pyrimidine.[Cayman Chemical]
Uses   Sepiapterin improved the endothelial dysfunction in SMA from db?/db mice by decreasing oxidative stress. Sepiapterin is commonly used in the study for treamtment of Type I Diabetes
Uses   Sepiapterin can be used to induce sequence-specific photolesions in double-stranded DNA.
Definition   ChEBI: L-sepiapterin is a sepiapterin with L configuration.
General Description   Sepiapterin, a pteridine derivative, is a stable precursor of tetrahydrobiopterin (BH4). It is a yellow pigment found in sepia mutant of Drosophila melanogaster and lemon Bombyx mori mutant (silkworm).
Biochem/physiol Actions   Cofactor of nitric oxide synthase; intracellularly converted to tetrahydro-biopterin leading to the stimulation of nitric oxide.
L-SEPIAPTERIN Preparation Products And Raw materials