2-[amidino(methyl)amino]acetic acid

Details:

Overview:

Creatine, also known as alpha-methylguanidine acetic acid, is a natural nutrient present in the human body and can also be synthesized from arginine, glycine and methionine in the liver, kidneys, pancreas: in the kidney arginine glycine transamidinase catalyzed by the transfer of arginine amidinogroup to the amino group of glycine, to produce guanidine acetic acid. In the liver, the methyltransferase of guanidine acetate catalyzes the transfer of S-adenosylmethionine methyl to guanidine acetate to produce creatine.

Physical and chemical properties:
Prismatic crystal (containing one molecule of crystal water). Melting point 303℃, relative density 1.33. Soluble in boiling water and 98% acetic acid, slightly soluble in ethanol, insoluble in ether and butyric acid. Creatinine is obtained by interaction with inorganic acid, methylamine is obtained by co-heating with alkali lime, ammonia is obtained by azeotrope with potassium hydroxide, and formidine oxalic acid and guanidine are obtained by interaction with potassium permanganate. In aqueous solution at room temperature, it reacts with mercury acetate to produce formiganyl glyoxylic acid, and finally formiganide and oxalic acid. The self-digestion of muscle juice or organ extracts is converted to creatinine.
Purpose:
Creatine can increase the water content of muscle cells, help muscle cells store energy, increase protein synthesis and other basic functions. Among them, the synthetic creatine can be used as a nutritional supplement to promote the skeletal muscle to adapt to intense exercise and to combat the excessive fatigue of weak individuals. It can also be used to prepare drugs for the treatment of heart disease and respiratory insufficiency; Preparation of pharmaceutical preparations containing human growth hormone; It can also be used to compound a new kind of health food, which has the effect of anti-aging and physical recovery.
Preparation method:
1. Using lime nitrogen as raw material to prepare creatine, there are three different process routes:
(1) Creatine is directly generated by the reaction of lime nitrogen with sodium sarcosine aqueous solution.
(2) Lime nitrogen reacts with methanol solution saturated with dry hydrogen chloride gas to produce O-methylisourea hydrochloride, which reacts with sarcosine to produce creatine.
(3) Lime nitrogen and hydrochloric acid aqueous solution under the condition of air to form chloramidine chloride, and then react with sarcosine sodium to get creatine.
2. Creatine monohydrate is obtained by the reaction of cyanamide with chloroacetic acid and methylamine.
3. Thiourea and dimethyl sulfate are used as raw materials to produce S-methylisothiourea sulfate, which is then reacted with sarcosine, sodium sarcosine or potassium sarcosine to creatine.
4. Using urea and dimethyl sulfate as raw materials to produce O-methylisourea sulfate, o-methylisourea sulfate reacts with sodium sarcosine to produce creatine monohydrate.
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Company Introduction

hebei yanxi chemical  co., LTD who registered capital of 10 million yuan, nearly to $2 million, we have a pharmaceutical raw materials factory production of pharmaceutical raw materials, and a reagent r&d center, and we do research and development production of reagent tens of thousands of species. our aim is quality strives for the survival. Seek development by credit reputation. Our products have big price advantage in Europe South America and so on .and Our company also has the advantage of high quality in Africa. in the past two years our products has reached more than 30 countries in the world, Europe. South America. North America, southeast Asia, Africa, etc. We welcome all over the world with the best quality and lowest price friend common cooperation and common development!

Our advantages

1) Timely communication, reply within 12 hours.You can leave any messages on our whats app or send email to us.

2)Selecting raw materials strictly,our products are the highest purity.

3)Reasonable and competitive price.

4) Free sample for your evaluation.Customers only need to undertake the shipping fee for delivery the samples to your destionation.

5)OEM/ODM Available.Trial order is available for testing after samples.

6) Packaging can be customized according to each buyers' special request.

We guarantee that your package will pass 100% through the Mexico US, UK, Australia, Netherlands, Canada, France, Germany, Spain, Belgium, Sweden, Poland, Russian, Ukraine, Kazakhstan, Czech Republic, Slovakia, Portugal.

We have freight forwarders in these countries, and our customs clearance company will clear your parcels without any customs issues, sometimes even 1000 kg. Door to door service. Make sure you receive 100% of the goods. Let you have a good experience of our strong freight capacity.

After Sales Service

1) Best quality in your requirement

2)Competitive price in china market

3)Mature technical support

4)Professional logistic support

5 )Full experience of large numberscontainers loading in chinese sea port

6 )Fast shipment by reputed shipping line

7) Packing with pallet as buyer's special request

8) Best service after shipment.

9) Cargoes together with container after-sales service available

10) Full experience in export

11)Raw materials from chinese origin

FAQ

1.What is the way you ship

Express: FedEx, UPS, EMS, DHL, USPS, TNT, DPD, Aramex etc

Our way of shipping the products is universal and secure.

The company name and other contents related to pharmacy are not written on the package slips.

The way of packing is regularly changed for a secure delivery.

The packages are small in order to avoid unwelcomed questions . If the order is big, then it will be divided into two or more packages

2.Can the packages be trackable

YES, we provide tracking number and you can track on internet.

3.Where do you ship to

Worldwide.

4.Do you offer domestic shipping/remail shipping

Yes we can ship to USA/UK/Canada/Australia/Germany etc warehouse first then to you.

5.Do you ensure your packing, what about customs, what happens if the package is retained

We concern a lot about our safety system, we pack the orders as secure as possible. If a package is seized at customs, reships of seized orders will be done provided you have a copy of the letter to show us. If you receive a seizure letter, please contact us immediately with a scanned copy of the seizure letter, and also a new address to have your order reshipped to.

6.Which payment options are available

Bitcoin,,Bank wire,MoneyGram

 

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