Nicotinamide riboside chloride NR-CL 23111-00-4
CAS NO. | 23111-00-4 |
MF | C11H15ClN2O5 |
MW | 290.7 |
EINECS NO. | 200-184-4 |
Solubility | Soluble up to 100mM in DMSO and up to 100mM in water |
Storage | under inert gas (nitrogen or Argon) at 2-8°C |
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Description
Nicotinamide riboside chloride/NR-CL(English abbreviated NRC) is an important precursor of coenzyme, also known as vitamin B3. This is the coenzyme nicotinamide adenine dinucleotide (NAD+, also known as coenzyme I), is a kind of a proton (hydrogen ion is more accurate) coenzyme, it appears in many metabolic reactions in cells. The decomposition of protein, carbohydrate and fat in compounds, the life activity of human body cannot do without this. With the aging of cells or lesions, it will reduce the number of. So, the NR-CL supplement can improve the coenzyme nicotinamide ribose, (NAD+) the basic content, improve the metabolic activity of the cells, thereby significantly improving the cell vitality, improve the physiological function of the human body various aspects.
Bulk nicotinamide riboside Nicotinamide Riboside is an all natural ingredient often found in milk products, and it has been known to have the benefit of helping with weight loss. Reviews reveal that it is one of the more popular supplements for boosting metabolism, increasing amounts of energy, and controlling diabetes.
The ingredient is not known to have any side effects associated with it as of the present. Another name that Nicotinamide Riboside can be called is Vitamin NR.
The NAD+ Precursor Nicotinamide Riboside Enhances Oxidative Metabolism and Protects against Hight-Fat Diet-Induced Obesity NR efficiently increases NAD+ levels in mammalian cells and tissues NR supplementation increases SIRT1 and SIRT3 activities NR largely prevents the detrimental metabolic effects of high-fat feeding NR enhances mitochondrial function and endurance performance.
NR-CL Function
1. Nicotinamide Riboside chloride/NR-CL can prevent pathological changes of skin and diseases of alimentary canal, such as dermatitis, black tongue, vomiting and diarrhea etc;
2. By participating in material and energy metabolism,Bulk Nicotinamide Riboside Powder can promote the body growth.
3. By combining with other medicines, Bulk Nicotinamide Riboside Powder can cure catarrh and ulcer;
4. Nicotinamide Riboside chloride/NR-CL improving the ability of blood supply with strong expansion function of blood vessel;
5. Nicotinamide Riboside chloride/NR-CL powder is highly effective in curing such diseases as dermatosis, hypercholesterolemia disease and coronary heart disease.
NR-CL Application:
Nicotinamide adenine dinucleotide (NAD+) has emerged as a critical co-substrate for enzymes involved in the beneficial effects of regular calorie restriction on healthspan. As such, the use of NAD+ precursors to augment NAD+ bioavailability has been proposed as a strategy for improving cardiovascular and other physiological functions with aging in humans. Here we provide the evidence in a 2 × 6-week randomized, double-blind, placebo-controlled, crossover clinical trial that chronic supplementation with the NAD+precursor vitamin, nicotinamide riboside (NR), is well tolerated and effectively stimulates NAD+metabolism in healthy middle-aged and older adults. Our results also provide initial insight into the effects of chronic NR supplementation on physiological function in humans, and suggest that, in particular, future clinical trials should further assess the potential benefits of NR for reducing blood pressure and arterial stiffness in this group.
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Zhengzhou strong peptide cross-border e-commerce Co., Ltd. is a high-tech chemical enterprise in Central China, specializing in the chemical raw materials and intermediates.Since its establishment, the company attaches great importance to team training and technical reform..Set research and development, production, testing, sales as one of the high-tech enterprises.The company is committed to the separation, purification and chiral separation of high purity natural products, as well as the development, production and marketing of API intermediates.The company mainly engaged in high-end monomer products of natural medicinal plants, semi-synthetic derivatives of medicinal plant ingredients, chemical synthetic products, high-end natural food and cosmetic additives.
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