Revefenacin / TD4208

Details:

Product Name: Revefenacin

CAS: 864750-70-9

MF: C35H43N5O4

MW: 597.75

Boiling point 777.5±60.0 °C(Predicted)

density 1.26±0.1 g/cm3(Predicted)

storage temp. Store at -20°C

solubility DMSO : ≥ 125 mg/mL (209.12 mM)

form Solid

pka 13.34±0.70(Predicted)

color White to off-white

Description Revefenacin is a synthetic anticholinergic that is prescribed for the treatment of chronic obstructive pulmonary disease (COPD).

Uses Revefenacin is used to treat chronic obstructive pulmonary disease (COPD), a long-term (chronic) lung disease that includes chronic bronchitis, emphysema, or both. It is an anticholinergic drug that helps the muscles around the airways in the lungs stay relaxed to prevent symptoms such as wheezing, coughing, chest tightness, and shortness of breath.

Application Revefenacin is an FDA-approved anticholinergic drug, a new tertiary amine biphenylcarbamate agent that also belongs to the long-acting muscarinic antagonist (LABA) family. It has the effect of relaxing the muscles around the airways of the lungs to make breathing easier. The structurally unstable tertiary amide produces a "soft drug" site, allowing rapid systemic clearance and minimising systemically mediated adverse effects. It can be used to treat symptoms such as wheezing, shortness of breath, cough and chest tightness in patients with chronic obstructive pulmonary disease (COPD: a group of diseases affecting the lungs and airways, including chronic bronchitis and emphysema).