CasNo.171887-03-9,N-(2-Amino-4,6-dichloro-5-pyrimidinyl) formamide,(171887-03-9) Suppliers

1 Kilogram	Negotiable

N-(2-Amino-4,6-dichloropyrimidin-5-yl)formamide Abacavir Sulfate 171887-03-9

Appearance:White crystallization
Application:treating pulmonary embolism and preventing recurrent deep vein thrombosis and pulmonary embolism in adults.
PackAge:25kg/drum
ProductionCapacity:10|Metric Ton|Day
Storage:
Transportation:AIR SEA TRAIN

We are very compeitive on Abacavir Sulfate .Our mfr is Chinese GMP certified for this item with DMF document.

Product Name:	N-(2-Amino-4,6-dichloro-5-pyrimidinyl)formamide
Synonyms:	N-(2-Amino-4.6-dichloro-5-pyrimdinyl) formamide;2-Amino-4,6-dichloro-5-pyrimidinyl formamide;2,5-Diamino-4,6-DichloroformamidoHcl;N-(2-Amino-4,6-Dichloro-5-Pyri;N-(2-AMINO-4,6-DICHLOROPYRIMIDIN-5-YL) FORMAMIDE[FOR ABACAVIR];N-(2-Amino-4,6-dichloro-5-pyrimidinyl)formamide;N-(2-Amino-4,6-dichloropyrimidin-5-yl)formamide;2-Amino-4,6-dichloro-5-formamidopyrimidine
CAS:	171887-03-9
MF:	C5H4Cl2N4O
MW:	207.02
EINECS:	425-650-6
Product Categories:	Heterocycle-Pyrimidine series;Bases & Related Reagents;Heterocycle;Heterocyclic Compounds;Heterocycles;Nucleotides;3
Mol File:	171887-03-9.mol

N-(2-Amino-4,6-dichloro-5-pyrimidinyl)formamide Chemical Properties

Melting point	>251°C (dec.)
Boiling point	554.8±60.0 °C(Predicted)
density	1.742±0.06 g/cm3(Predicted)
storage temp.	under inert gas (nitrogen or Argon) at 2–8 °C
solubility	DMSO, Methanol
form	Solid
pka	10.90±0.70(Predicted)
color	Off-White to Pale Beige
CAS DataBase Reference	171887-03-9(CAS DataBase Reference)

Safety Information

HS Code

2933.59.9500

Chemical Properties	White crystalline powder
Uses	N-(2-Amino-4,6-dichloro-5-pyrimidinyl)formamide (Abacavir - In House Impurity) is an intermediate of Abacavir (A105000). Abacavir is a carbocyclic 2''-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection (1). Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA (2). Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively.
Uses	Abacavir intermediate. A purine derivative
Uses	Prasugrel intermediate