Hydratropicacid (6CI,7CI,8CI) (RS)-2-Phenylpropanoic acid Hydratropic acid
2-Phenylpropionic acid is used in the preparation of ibuprofen derivatives for their anti-inflammatory activity. Also used in nucleation inhibitors in Dutch resolution of diastereomers.
2-Phenylpropionic acid is prepared:
1) from Benzyl cyanide by Metbylation with Methyl iodide and Sodamide to produce alpha-Phenylpropionitrile, from which the acid is produced by acid hydrolysis.2) from Acetophenone cyanhydrin with Hydriodic acid.
ChEBI: A 2-arylpropionic acid carrying a phenyl group at position 2. It is a metabolite of alpha-methylstyrene (AMS), a volatile hydrocarbon.
2-Phenylpropionic acid is used in the preparation of ibuprofen derivatives for their anti-inflammatory activity. Also used in nucleation inhibitors in Dutch resolution of diastereomers.
2-Phenylpropionic acid is prepared:
1) from Benzyl cyanide by Metbylation with Methyl iodide and Sodamide to produce alpha-Phenylpropionitrile, from which the acid is produced by acid hydrolysis.2) from Acetophenone cyanhydrin with Hydriodic acid.
ChEBI: A 2-arylpropionic acid carrying a phenyl group at position 2. It is a metabolite of alpha-methylstyrene (AMS), a volatile hydrocarbon.
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