C8H16O5 868156-46-1 (S)-Pro-xylane
(S)-Pro-xylane Basic information
Product Name: (S)-Pro-xylane
Synonyms: (S)-Pro-xylane (Synonyms: (S)-Hydroxypropyl tetrahydropyrantriol);(S)-Pro-xylane;L-glycero-L-gluco-Octitol, 1,5-anhydro-6,8-dideoxy-;βS2018;(S)-Pro xylane,Hydroxypropyl tetrahydropyrantriol;(S)-Hydroxypropyl tetrahydropyrantriol;Hydroxypropyl tetrahydropyranetriol;Xylose Impurity 14
CAS: 868156-46-1
MF: C8H16O5
MW: 192.21
EINECS: 456-880-5
Product Categories: 868156-46-1;1
Mol File: 868156-46-1.mol
Boiling point 376.0±42.0 °C(Predicted)
density 1.368±0.06 g/cm3(Predicted)
storage temp. 4°C, away from moisture and light
solubility DMSO: 250 mg/mL (1300.66 mM)
pka 13.55±0.70(Predicted)
form Solid
color White to off-white
InChI InChI=1/C8H16O5/c1-4(9)2-6-8(12)7(11)5(10)3-13-6/h4-12H,2-3H2,1H3/t4-,5+,6-,7-,8-/s3
InChIKey KOGFZZYPPGQZFZ-FHYXRTTRNA-N
SMILES C([C@@H]1OC[C@@H](O)[C@H](O)[C@H]1O)[C@@H](O)C |&1:1,4,6,8,10,r|
Description (S)-Pro-xylane is the S-enantiomer of Pro-xylane. Pro-xylane, a biologically active C-glycoside in aqueous media, acts as an activator of glycosaminoglycans (GAGs) biosynthesis.
Synthesis In the autoclave, add 461g of intermediate 2,5 liters of isopropanol sequentially, seal the autoclave, replace the nitrogen 3 times, hydrogen displace 1 time, and then dissolve the catalyst [RuCl(cymene)(S-BINAP)] Cl (300mg) in 300mL of isopropanol solution underH2atmosphere, carefully add it to the autoclave, continue to fill hydrogen to 50kgf/cm2, and then heat up to about 60 °C, After stirring the reaction for 6h, stop the reaction, remove the material, and cool down the crystals to obtain βS-type Boseine products.The final product (S)-Pro-xylane can be obtained.
(S)-Pro-xylane Basic information
Product Name: (S)-Pro-xylane
Synonyms: (S)-Pro-xylane (Synonyms: (S)-Hydroxypropyl tetrahydropyrantriol);(S)-Pro-xylane;L-glycero-L-gluco-Octitol, 1,5-anhydro-6,8-dideoxy-;βS2018;(S)-Pro xylane,Hydroxypropyl tetrahydropyrantriol;(S)-Hydroxypropyl tetrahydropyrantriol;Hydroxypropyl tetrahydropyranetriol;Xylose Impurity 14
CAS: 868156-46-1
MF: C8H16O5
MW: 192.21
EINECS: 456-880-5
Product Categories: 868156-46-1;1
Mol File: 868156-46-1.mol
Boiling point 376.0±42.0 °C(Predicted)
density 1.368±0.06 g/cm3(Predicted)
storage temp. 4°C, away from moisture and light
solubility DMSO: 250 mg/mL (1300.66 mM)
pka 13.55±0.70(Predicted)
form Solid
color White to off-white
InChI InChI=1/C8H16O5/c1-4(9)2-6-8(12)7(11)5(10)3-13-6/h4-12H,2-3H2,1H3/t4-,5+,6-,7-,8-/s3
InChIKey KOGFZZYPPGQZFZ-FHYXRTTRNA-N
SMILES C([C@@H]1OC[C@@H](O)[C@H](O)[C@H]1O)[C@@H](O)C |&1:1,4,6,8,10,r|
Description (S)-Pro-xylane is the S-enantiomer of Pro-xylane. Pro-xylane, a biologically active C-glycoside in aqueous media, acts as an activator of glycosaminoglycans (GAGs) biosynthesis.
Synthesis In the autoclave, add 461g of intermediate 2,5 liters of isopropanol sequentially, seal the autoclave, replace the nitrogen 3 times, hydrogen displace 1 time, and then dissolve the catalyst [RuCl(cymene)(S-BINAP)] Cl (300mg) in 300mL of isopropanol solution underH2atmosphere, carefully add it to the autoclave, continue to fill hydrogen to 50kgf/cm2, and then heat up to about 60 °C, After stirring the reaction for 6h, stop the reaction, remove the material, and cool down the crystals to obtain βS-type Boseine products.The final product (S)-Pro-xylane can be obtained.
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