Vilanterol Trifenatate (API) 503070-58-4 GW642444M
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Product Name: Vilanterol Trifenatate
503070-58-4
CAS: 503070-58-4
MF: C44H49Cl2NO7
MW: 774.78
EINECS: 638-763-2
Melting point 131.9-134.2℃
storage temp. Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility Dichloromethane (Slightly), Methanol (Slightly)
form Solid
color White to Off-White
Stability: Hygroscopic
Chemical Properties Vilanterol trifenatate is a white powder with a molecular weight of 774.8, and the empirical formula is C24H33Cl2NO5.C20H16O2. It insoluble in water and slightly soluble in methanol, ethanol, acetonitrile and propan-2-ol. It is slightly hygroscopic. It is provided in a micronized form.
Uses Vilanterol Trifenatate is a long-acting β2 adrenergic receptor Agonist with alonger than 24-hour activity in humans, and is being developed to be used in combination with FF. It is also highly selective for the β2-receptor, with over 1000-fold greater selectivity compared to β1-receptors. It demonstrates prolonged bronchodilation in subjects with asthma and COPD.
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