J 147 1146963-51-0 Pharmaceuticals
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J-147
Factory Supply J 147 J-147 Powder Cas 1146963-51-0
J-147 cas 1146963-51-0
2,2,2-Trifluoroacetic acid 1-(2,4-DiMethylphenyl)-2-[(3-Methoxyphenyl)Methylene]hydrazide
MF: C18H17F3N2O2
MW: 350.33
CAS: 1146963-51-0
EINECS 1592732-453-0
Boiling point 412.8±55.0°C(Predicted)
density 1.18±0.1g/cm3(Predicted)
Storage condition Sealedindry,RoomTemperature
solubility DMSO:68.0(MaxConc.mg/mL);194.1(MaxConc.mM)
Form Powder
Purity: 99%
Apperance: White to Off-white Powder
What is J-147?
J-147 is a novel neurotrophic drug for cognitive enhancement and Alzheimer's disease. J-147 is an exceptionally potent, orally active and broadly neuroprotective compound has the ability to enhance memory in normal animals as well as to prevent memory deficits in Alzheimer's disease (AD) transgenic mice. The neurotrophic and memory-enhancing activities of J-147 are associated with an increase in brain derived neurotrophic factor (BDNF) levels and the expression of BDNF responsive proteins, the enhancement of LTP, the preservation of synaptic protein, the reduction of amyloid plaques.
1. J-147 can improve memory;
2. J-147 can improve the brain function;
3. J-147 can prevent and treat senile dementia;
4. J-147 can enhance the learning ability;
5. J-147 can increase the attention;
6. J-147 can eelieve the anxiety.
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