CasNo.50-42-0,Adiphenine hydrochloride,(50-42-0) Suppliers

1 Gram	Negotiable

Min.Order :1 Gram
Purity: 99%
Payment Terms : T/T

Keywords

Aceticacid, diphenyl-, 2-(diethylamino)ethyl ester hydrochloride (8CI) Benzeneaceticacid, a-phenyl-, 2-(diethylamino)ethylester, hydrochloride (9CI) 2-Diethylaminoethyl diphenylacetate hydrochloride

Quick Details

Appearance:white solid
Application:2-(Diethylamino)ethyla-phenylbenzeneacetatehydrochloride;Disodium(6E)-4-amino-3-(4-nitrophenyl)diazenyl-5-oxo-6-(phenylhydrazinylidene)naphthalene-2,7-disulfonateChemicalbook;OilBlackS;OrientWaterBlac
PackAge:according to the customer
ProductionCapacity:1|Metric Ton|
Storage:Room Temperature
Transportation:by sea air and courier

Superiority:

InvitrostudiesAdiphenine(10nM-1mM;3min)blocksthefunctionofα1*-nAChRinadose-dependentmannerinTE671/RDcells,withanIC50of1.9µM.Adiphenine(10nM-1mM;3min)blocksthefunctionofα3α4*-nAChRinadose-dependentmannerinSH-SY5Ycells,withanIC50of1.8µM.Adiphenine(10nM-1mM;3min)blocksthefunctionofα4β2-andα4β4-nAChRinChemicalbookadose-dependentmannerinSH-EP1cells,withIC50sof3.7and6.3µM,respectively.Adiphenine(50-200µM;30-60s)decreasesthefrequencyofACh-inducedsingle-channelcurrentsinHEK293cells.InvivostudiesAdiphenine(i.p.)preventsthehindlegtonic-extensorcomponentofmaximalelectroshockseizures(MES),withanED50of62mg/kginmice.InvitrostudiesAdiphenine(10nM-1mM;3min)blocksthefunctionofα1*-nAChRinadose-dependentmannerinTE671/RDcells,withanIC50of1.9µM.Adiphenine(10nM-1mM;3min)blocksthefunctionofα3α4*-nAChRinadose-dependentmannerinSH-SY5Ycells,withanIC50of1.8µM.Adiphenine(10nM-1mM;3min)blocksthefunctionofα4β2-andα4β4-nAChRinChemicalbookadose-dependentmannerinSH-EP1cells,withIC50sof3.7and6.3µM,respectively.Adiphenine(50-200µM;30-60s)decreasesthefrequencyofACh-inducedsingle-channelcurrentsinHEK293cells.InvivostudiesAdiphenine(i.p.)preventsthehindlegtonic-extensorcomponentofmaximalelectroshockseizures(MES),withanED50of62mg/kginmice.

Details:

InvitrostudiesAdiphenine(10nM-1mM;3min)blocksthefunctionofα1*-nAChRinadose-dependentmannerinTE671/RDcells,withanIC50of1.9µM.Adiphenine(10nM-1mM;3min)blocksthefunctionofα3α4*-nAChRinadose-dependentmannerinSH-SY5Ycells,withanIC50of1.8µM.Adiphenine(10nM-1mM;3min)blocksthefunctionofα4β2-andα4β4-nAChRinChemicalbookadose-dependentmannerinSH-EP1cells,withIC50sof3.7and6.3µM,respectively.Adiphenine(50-200µM;30-60s)decreasesthefrequencyofACh-inducedsingle-channelcurrentsinHEK293cells.InvivostudiesAdiphenine(i.p.)preventsthehindlegtonic-extensorcomponentofmaximalelectroshockseizures(MES),withanED50of62mg/kginmice.InvitrostudiesAdiphenine(10nM-1mM;3min)blocksthefunctionofα1*-nAChRinadose-dependentmannerinTE671/RDcells,withanIC50of1.9µM.Adiphenine(10nM-1mM;3min)blocksthefunctionofα3α4*-nAChRinadose-dependentmannerinSH-SY5Ycells,withanIC50of1.8µM.Adiphenine(10nM-1mM;3min)blocksthefunctionofα4β2-andα4β4-nAChRinChemicalbookadose-dependentmannerinSH-EP1cells,withIC50sof3.7and6.3µM,respectively.Adiphenine(50-200µM;30-60s)decreasesthefrequencyofACh-inducedsingle-channelcurrentsinHEK293cells.InvivostudiesAdiphenine(i.p.)preventsthehindlegtonic-extensorcomponentofmaximalelectroshockseizures(MES),withanED50of62mg/kginmice.