Cefmetazole sodium

Cefmetazole sodium

Cefmetazole sodium

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1 Gram

Negotiable

  • Min.Order :1 Gram
  • Purity: 99%
  • Payment Terms : T/T

Keywords

Cefmetazole sodium 56796-39-5 99%

Quick Details

  • Appearance:white powder
  • Application:INTERMEDITD
  • PackAge:According to your needs
  • ProductionCapacity:100|Metric Ton|Year
  • Storage:Inert atmosphere,2-8°C
  • Transportation:Courier Air Sea

Superiority:

Cefmetazole sodium Basic information
Product Name: Cefmetazole sodium
Synonyms: Cefmetazone;5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[[(cyanomethyl)thio]acetyl]amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-, monosodium salt, (6R,7S)-;5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[[(cyanomethyl)thio]acetyl]amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-, monosodium salt, (6R-cis)-;Cefmetazole-Na;CS-1170 sodium salt;Metafar;Sodium cefmetazole;(6R,7S)-7-[[2-[(Cyanomethyl)thio]acetyl]amino]-7-methoxy-3-[[(1-methyl -1H-tetrazol-5-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene -2-carboxylic Acid Sodium Salt
CAS: 56796-39-5
MF: C15H18N7NaO5S3
MW: 495.52
EINECS: 627-393-7
Product Categories: Sulfur & Selenium Compounds;A - KAntibiotics;Antibacterial;Antibiotics A to;Antibiotics A-FAntibiotics;Chemical Structure Class;Chiral Reagents;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Interferes with Cell Wall SynthesisAntibiotics;Mechanism of Action;Penicillins and Cephalosporins (beta-Lactams);Spectrum of Activity
Mol File: 56796-39-5.mol

Details:

Cefmetazole sodium Chemical Properties
Melting point     >130°C (dec.)
storage temp.     Inert atmosphere,2-8°C
solubility     H2O: soluble50mg/mL
form     powder
color     White to Off-White
Water Solubility     Soluble in water
Sensitive     Hygroscopic
Merck     14,1926
Stability:    Hygroscopic
InChIKey    BITQGIOJQWZUPL-PBCQUBLHSA-M
CAS DataBase Reference    56796-39-5(CAS DataBase Reference)
Safety Information
Hazard Codes     Xn,Xi
Risk Statements     36/37/38-42/43
Safety Statements     26-36
WGK Germany     2
RTECS     XI0372200
HS Code     2941.90.3000
Toxicity    LD50 i.v. in rats: >5000 mg/kg (Masuda)
MSDS Information
Cefmetazole sodium Usage And Synthesis
Chemical Properties    White Solid
Uses    Semi-synthetic antibiotic derived from Cephamycin. Antibacterial
Uses    Cefmetazole sodium is used clinically in combination with Tanreqing for the treatment of Pulmonary infections like Senile Emphysema and other acute bacterial infections.
Definition    ChEBI: An organic sodium salt that is the sodium salt of cefmetazole.
Brand name    Zefazone (Pharmacia & Upjohn).
Clinical Use    Cefmetazole (Zefazone) is a semisynthetic, third-generation,parenteral cephalosporin of the cephamycin group. Likeother cephamycins, the presence of the 7α-methoxyl groupconfers resistance to many β-lactamases. Cefmetazoleexhibits significantly higher potency against members ofthe Enterobacteriaceae family but lower activity againstBacteroides spp. than cefoxitin. It is highly active againstN. gonorrhoeae, including -lactamase–producing strains. Incommon with other cephamycins, cefmetazole is ineffectiveagainst indole-positive Proteus, Enterobacter, Providencia,Serratia, and Pseudomonas spp. Cefmetazole has the MTTmoiety associated with increased bleeding in certain highriskpatients. It has a plasma half-life of 1.1 hours.

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