Cefmenoxime hydroch...

Cefmenoxime hydrochloride

Cefmenoxime hydrochloride

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  • Purity: 99%
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Cefmenoxime hydrochloride 75738-58-8 99%

Quick Details

  • Appearance:white solid
  • Application:INTERMEDITD
  • PackAge:According to ypur needs
  • ProductionCapacity:100|Metric Ton|Year
  • Storage:under inert gas (nitrogen or Argon) at 2-8°C
  • Transportation:Courier Air Sea

Superiority:

Cefmenoxime hydrochloride Basic information

 

Product Name: Cefmenoxime hydrochloride
Synonyms: 8-[2-(2-amino-1,3-thiazol-4-yl)-2-methoxyimino-acetyl]amino-4-[(1-methyltetrazol-5-yl)sulfanylmethyl]-7-oxo-2-thia-6-azabicyclo[4.2.0]oct-4-ene-5-carboxylic acid hydrochloride (2:1);7-[[(2-Amino-4-thiazolyl)(methoxyimino)acetyl]amino]-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid hemihydrochloride;7beta-[2-(2-Aminothiazol-4-yl)-(Z)-2-(methoxyiminoacetamido)]-3-[(1-methyl-1H-tetrazol-5-yl)thiomethyl]ceph-3-em-4-carboxylic acid hemihydrochloride;Bestcall;Bestron;Cemix;SCE-1365(free acid);Tacef
CAS: 75738-58-8
MF: C16H18ClN9O5S3
MW: 548.01
EINECS: 278-299-4
Product Categories: CEFMAX;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Sulfur & Selenium Compounds
Mol File: 75738-58-8.mol

Details:

Cefmenoxime hydrochloride Chemical Properties
Melting point  >175°C (dec.)
storage temp.  under inert gas (nitrogen or Argon) at 2-8°C
solubility  DMSO (Slightly, Heated), Methanol (Slightly)
form  Solid
color  Off-White to Pale Yellow
InChIKey HZYJYGJIOCXOTH-AJVJENPNNA-N
SMILES C(C1=C(CS[C@]2([H])[C@H](NC(=O)/C(/C3N=C(N)SC=3)=N\OC)C(=O)N12)CSC1=NN=NN1C)(=O)O.Cl |&1:5,7,r|
 
Safety Information
HS Code  2941906000
MSDS Information
 
Cefmenoxime hydrochloride Usage And Synthesis
Description Cef menoxime hydrochloride is a third generation cephalosporin antibiotic. Structurally, it possesses the (1-methyl-lH-tetrazol-5-yl)thiomethyl moiety in the 3-position; like several other compounds containing this structural element (moxalactam, cefoperazone, cefamandol), bleeding linked to vitamin K interaction has been reported. Cefmenoxime has activity similar to cefotiuime, ceftizoxime and moxalactam against E.coli, C. diversus, Klebsiella, P. Mirabilis, Salmonella, Shigella, Neiseria spp., S. pyogenes, S. Pneumoniae, and g. influenzae. It is relatively ineffective against Pseudomonas and Bacteroidea.
Originator Takeda (Japan)
Uses A third generation cephalosporin antibiotic with strong antimicrobial activities against Streptococcus pneumoniae, Haemophilus influenzae and Moraxella subgenus Branhamella catarrhalis that were 3 major aerobic bacteria from sinusitis.
Uses antibacterial
Definition ChEBI: The hemihydrochloride salt of cefmenoxime.
Brand name Cefmax (TAP);TACEF;BESTCALL.
General Description Cefmenoxime was synthesized by Takeda Pharmaceutical Co. in 1978. It contains aminothiazole and methoxyimino groups in the 7-acyl position and a methyltetrazole group at the 3 position of the cephem nucleus. Cefmenoxime has a wide activity spectrum against gram-positive and gram-negative bacteria, including anaerobes, except Staphylococcus aureus. Cefmenoxime is a member of the so-called third-generation cephalosporins, a recently introduced class of clinically important antibiotics.

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