ARTICAINE CAS 23964-58-1

Details:

Articaine hydrochloride is used for relief of pain in minor operations, usually in combination with the vasoconstrictor. from NCIt. A thiophene-containing local anesthetic pharmacologically similar to MEPIVACAINE. from MeSH.
Articaine Hydrochloride is the hydrochloride salt form of articaine, an amide-type local anesthetic. Articaine hydrochloride reversibly blocks nerve impulse conduction by binding to specific membrane sodium ion channels thereby interfering with the electrical excitation in the nerve, slowing the propagation of the nerve impulse and reducing the rate of rise of the action potential. This results in a loss of sensation at the injection site. Articaine hydrochloride is used for relief of pain in minor operations, usually in combination with the vasoconstrictor.

Application & Function
Articaine hydrochloride is used for relief of pain in minor operations, usually in combination with the vasoconstrictor.
Application
Articaine is a local anaesthetic that has been approved overseas for several years. Like other amide anaesthetics, articaine blocks nerve conduction when it is infiltrated around a nerve. This action is prolonged by combining the drug with a vasoconstrictor such as adre.The combination of articaine and adre can be used for local or regional anaesthesia for dental procedures. Anaesthesia begins within six minutes and lasts for an hour. The half-life of articaine is approximately 1.8 hours. It is metabolised and then mainly excreted in the urine.

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