Superiority:

Chemical Safety Data Sheet MSDS / SDS

L-Glutamine

Revision Date:2024-08-24Revision Number:1

SECTION 1: Identification of the substance/mixture and of the company/undertaking

Product identifier

• Product name: L-Glutamine
• CBnumber: CB6280105
• CAS: 56-85-9
• EINECS Number: 200-292-1
• Synonyms: L-Glutamine,Glutamine

Relevant identified uses of the substance or mixture and uses advised against

• Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
• Uses advised against: none

 

SECTION 2: Hazards identification

GHS Label elements, including precautionary statements

• Signal wordNo signal word

Hazard statement(s)

none

Prevention

none

Response

none

Storage

none

Disposal

none

SECTION 3: Composition/information on ingredients

Substance

• Product name: L-Glutamine
• Synonyms: L-Glutamine,Glutamine
• CAS: 56-85-9
• EC number: 200-292-1
• MF: C5H10N2O3
• MW: 146.14

SECTION 4: First aid measures

Description of first aid measures

If inhaled

If breathed in, move person into fresh air. If not breathing, give artificial respiration.

In case of skin contact

Wash off with soap and plenty of water.

In case of eye contact

Flush eyes with water as a precaution.

If swallowed

Never give anything by mouth to an unconscious person. Rinse mouth with water.

Most important symptoms and effects, both acute and delayed

The most important known symptoms and effects are described in the labelling (see section 2.2) and/or in section 11

Indication of any immediate medical attention and special treatment needed

No data available

SECTION 5: Firefighting measures

Extinguishing media

Suitable extinguishing media

Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.

Special hazards arising from the substance or mixture

Carbon oxides, Nitrogen oxides (NOx)

Advice for firefighters

Wear self-contained breathing apparatus for firefighting if necessary.

Further information

No data available

NFPA 704

2

0

0

	HEALTH	2	Intense or continued but not chronic exposure could cause temporary incapacitation or possible residual injury (e.g. diethyl ether, ammonium phosphate, iodine)
	FIRE	0	Materials that will not burn under typical fire conditions, including intrinsically noncombustible materials such as concrete, stone, and sand. Materials that will not burn in air when exposed to a temperature of 820 °C (1,500 °F) for a period of 5 minutes.(e.g. Carbon tetrachloride)
	REACT	0	Normally stable, even under fire exposure conditions, and is not reactive with water (e.g. helium,N2)
	SPEC. HAZ.

SECTION 6: Accidental release measures

Personal precautions, protective equipment and emergency procedures

Avoid dust formation. Avoid breathing vapours, mist or gas. For personal protection see section 8.

Environmental precautions

No special environmental precautions required.

Methods and materials for containment and cleaning up

Sweep up and shovel. Keep in suitable, closed containers for disposal.

Reference to other sections

For disposal see section 13.

SECTION 7: Handling and storage

Precautions for safe handling

Provide appropriate exhaust ventilation at places where dust is formed. For precautions see section 2.2.

Conditions for safe storage, including any incompatibilities

Keep container tightly closed in a dry and well-ventilated place. Store in cool place.

Specific end use(s)

Apart from the uses mentioned in section 1.2 no other specific uses are stipulated

SECTION 8: Exposure controls/personal protection

control parameter

Hazard composition and occupational exposure limits

Does not contain substances with occupational exposure limits.

Exposure controls

Appropriate engineering controls

General industrial hygiene practice.

Personal protective equipment

Eye/face protection

Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection

Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands.

The selected protective gloves have to satisfy the specifications of Regulation (EU) 2016/425 and the standard EN 374 derived from it.

Full contact

Material: Nitrile rubber

Minimum layer thickness: 0,11 mm Break through time: 480 min

Material tested:Dermatril? (KCL 740 / Aldrich Z677272, Size M)

Splash contact Material: Nitrile rubber

Minimum layer thickness: 0,11 mm Break through time: 480 min

Material tested:Dermatril? (KCL 740 / Aldrich Z677272, Size M)

data source: KCL GmbH, D-36124 Eichenzell, phone +49 (0)6659 87300, e-mail sales@kcl.de, test method: EN374

If used in solution, or mixed with other substances, and under conditions which differ from EN 374, contact the supplier of the CE approved gloves. This recommendation is advisory only and must be evaluated by an industrial hygienist and safety officer familiar with the specific situation of anticipated use by our customers. It should not be construed as offering an approval for any specific use scenario.

Body Protection

Choose body protection in relation to its type, to the concentration and amount of dangerous substances, and to the specific work-place., The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.

Respiratory protection

Respiratory protection is not required. Where protection from nuisance levels of dusts are desired, use type N95 (US) or type P1 (EN 143) dust masks. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).

Control of environmental exposure

No special environmental precautions required.

SECTION 9: Physical and chemical properties

Information on basic physicochemical properties

• Appearancewhite powder
• OdourNo data available
• Odour ThresholdNo data available d) pH 5,0 - 6 at 14,6 g/l at 25 °C Melting point/freezing point Initial boiling point and boiling range Melting point/range: 185 °C No data available Flash point No data available Evaporation rate No data available Flammability (solid, gas) Upper/lower flammability or explosive limits No data available No data available Vapour pressure No data available Vapour density No data available Relative density No data available Water solubility 14,6 g/l at 20 °C - completely soluble Partition coefficient: n-octanol/water Autoignition temperature Decomposition temperature log Pow: -4,609 No data available No data available Viscosity No data available Explosive properties No data available Oxidizing properties No data available
• Melting point/freezing pointMelting point/range: 185 °C
• Initial boiling point and boiling range185 °C (dec.) (lit.)
• Flash point265.74°C (rough estimate)
• Evaporation rate185°C
• Flammability (solid, gas)No data available
• Upper/lower flammability or explosive limitsNo data available
• Vapour pressureNo data available
• Vapour densityNo data available
• Relative densityNo data available
• Water solubility14,6 g/l at 20 °C - completely soluble
• Partition coefficient: n-octanol/waterlog Pow: -4,609
• Autoignition temperatureNo data available
• Decomposition temperatureNo data available
• Viscosity185 ºC
• Explosive propertiesNo data available
• Oxidizing propertiesNo data available
• λmaxλ: 260 nm Amax: 0.01
  λ: 280 nm Amax: 0.01

Other safety information

No data available

SECTION 10: Stability and reactivity

Reactivity

No data available

Chemical stability

Stable under recommended storage conditions.

Possibility of hazardous reactions

No data available

Conditions to avoid

No data available

Incompatible materials

Strong oxidizing agents

Hazardous decomposition products

Hazardous decomposition products formed under fire conditions. - Carbon oxides, Nitrogen oxides (NOx)

Other decomposition products - No data available In the event of fire: see section 5

SECTION 11: Toxicological information

Information on toxicological effects

Acute toxicity

LD50 Oral - Rat - male and female - > 16.000 mg/kg Remarks: (ECHA)

Skin corrosion/irritation

Skin - Rabbit
Result: No skin irritation - 4 h (OECD Test Guideline 404)
Remarks: (in analogy to similar products)

Serious eye damage/eye irritation

Eyes - Rabbit
Result: No eye irritation (OECD Test Guideline 405)
Remarks: (in analogy to similar products)

Respiratory or skin sensitisation

No data available

Germ cell mutagenicity

Mutagenicity (mammal cell test): chromosome aberration. Chinese hamster lung cells
Result: negative (ECHA)
Ames test
Escherichia coli/Salmonella typhimurium Result: negative
(ECHA)

Carcinogenicity

IARC: No component of this product present at levels greater than or equal to 0.1% is identified as probable, possible or confirmed human carcinogen by IARC.

Reproductive toxicity

No data available

Specific target organ toxicity - single exposure

No data available

Specific target organ toxicity - repeated exposure

No data available

Aspiration hazard

No data available

Additional Information

Repeated dose toxicity - Rat - male and female - Oral - 90 d - No observed adverse effect level - 833 - 964 mg/kg
Subchronic toxicity (ECHA) RTECS: MA2275100
To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated.
Hazardous properties cannot be excluded but are unlikely when the product is handled appropriately.
Substances which occur in nature
Handle in accordance with good industrial hygiene and safety practice.

Toxicity

LD50 orally in Rabbit: 7500 mg/kg

SECTION 12: Ecological information

Toxicity

No data available

 

Toxicity to daphnia and other aquatic invertebrates

 

semi-static test EC50 - Daphnia magna (Water flea) - > 100 mg/l - 48 h

(OECD Test Guideline 202)

 

Toxicity to algae

Growth inhibition ErC50 - Desmodesmus subspicatus (green algae) -

 

> 100 mg/l - 72 h

(OECD Test Guideline 201)

Persistence and degradability

Biodegradability Result: 77 % - Readily biodegradable.

(OECD Test Guideline 301C)

Bioaccumulative potential

No data available

Mobility in soil

No data available

Results of PBT and vPvB assessment

This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.

Other adverse effects

No data available

SECTION 13: Disposal considerations

Waste treatment methods

Product

Offer surplus and non-recyclable solutions to a licensed disposal company.

Contaminated packaging

Dispose of as unused product.

SECTION 14: Transport information

UN number

ADR/RID: - IMDG: - IATA: -

UN proper shipping name

ADR/RID: Not dangerous goods IMDG: Not dangerous goods IATA: Not dangerous goods

Transport hazard class(es)

ADR/RID: - IMDG: - IATA: -

Packaging group

ADR/RID: - IMDG: - IATA: -

Environmental hazards

ADR/RID: no IMDG Marine pollutant: no IATA: no

Special precautions for user

No data available

SECTION 15: Regulatory information

Safety, health and environmental regulations/legislation specific for the substance or mixture

Regulations on the Safety Management of Hazardous Chemicals

China Catalog of Hazardous chemicals 2015:Not Listed. website: #

Measures for Environmental Management of New Chemical Substances

Chinese Chemical Inventory of Existing Chemical Substances (China IECSC):Listed. website: #

EC Inventory:Listed.

European Inventory of Existing Commercial Chemical Substances (EINECS):Listed. website: #

Korea Existing Chemicals List (KECL):Listed. website: //ncis.nier.go.kr

New Zealand Inventory of Chemicals (NZIoC):Listed. website: #

Philippines Inventory of Chemicals and Chemical Substances (PICCS):Listed. website: #

United States Toxic Substances Control Act (TSCA) Inventory:Listed. website: #

Vietnam National Chemical Inventory:Listed. website: #

SECTION 16: Other information

Abbreviations and acronyms

• ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
• CAS: Chemical Abstracts Service
• EC50: Effective Concentration 50%
• IATA: International Air Transportation Association
• IMDG: International Maritime Dangerous Goods
• LC50: Lethal Concentration 50%
• LD50: Lethal Dose 50%
• RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
• STEL: Short term exposure limit
• TWA: Time Weighted Average

Package&Shipping