Details:

Our advantage:

1. High quality with competitive price:

1) Standard:BP/USP/EP/Enterprise standard

2) All Purity≥99%

3) We are manufacturer and can provide high quality products with factory price.

 2, Fast and safe delivery

1) Parcel can be sent out in 24 hours after payment.Tracking number available

2) Secure and discreet shipment.Various transportation methods for your choice.

3) Customs pass rate ≥99%

4) We have our own agent/remailer/distributor who can help us ship our products very fast and safe,

and we have stock in there for transferring.

Water Solubility	soluble
Storage Condition	2-8℃
MDL	MFCD00081423
Physical and Chemical Properties	Bromelain is a proteolytic enzyme extracted from pineapple juice or pineapple waste skin, referred to as pineapple enzyme. It is a light yellow amorphous powder. Slightly soluble in water, insoluble in ethanol, acetone, chloroform, ether. The optimum pH is 7. Slightly stinky. Enzyme activity can be activated by bovine cystine and inhibited by heavy metals. The preparation of pineapple enzyme is enteric-coated tablets, which appear grayish brown after removing the casing. Compound pineapple enzyme tablets are enteric-coated tablets of pineapple enzyme and pig bile extract powder, which show gray brown after removing the casing.

Product Packaging：

1) 1kg/bag (1kg net weight, 1.1kg gross weight, packed in an aluminum foil bag)

2) 25kg/drum (25kg net weight, 28kg gross weight; Packed in a cardboard-drum with two plastic-bags inside; Drum Size: 510mm high, 360mm diameter)

 Storage：

Stored in a cool and dry well-closed container. Keep away from moisture and strong light/heat.

Delivery：

Usually within3-5 working days after full payment.

transport：

EMS,DHL, TNT, UPS ,FEDEX, BY AIR, BY SEA

DHL Express, FedEx and EMS for quantity less than 50KG, usually called as DDU service; 

Sea shipping for quantity over 500KG; And air shipping is available for 50KG above;

For high value products, please select air shipping and DHL express for safe;

Our Service:
1. Fast Delivery: We can delivery within 24 hours upon receipt of your payment.
2. Quality can be promised. Hot sell to Worldwide.
3. Payment Terms: T/T,, t/t
4. Free Sample available at any time.
5. Tracking your order at any time. Inform your order's further new situation at any time.
6. Package: Professional packing with professional materials.

Open Data Verified Data

• a proteolytic enzyme, referred to as pineapple enzyme, extracted from pineapple juice or pineapple waste skin. It is a light yellow amorphous powder with slightly abnormal odor. Slightly soluble in water, insoluble in ethanol, acetone, chloroform, ether. The optimum pH was 7 and the molecular weight was 33000.
• It is a thiol enzyme with anti-inflammatory and anti-edema effects. Enzyme activity can be activated by bovine cystine, and by heavy metal inhibition. It can hydrolyze fibrin, casein and hemoglobin, dissolve fibrin and blood clots, improve body fluid circulation, increase tissue permeability, and lead to the regression of inflammation, edema and hematoma. It is characterized by the breakdown of large molecules of fibrin, but does not destroy fibrinogen necessary for coagulation. Combined with chemotherapy drugs, can promote the penetration and diffusion of the drug to the lesion, thereby enhancing the efficacy. Unlike papain, this product can break down muscle fibers.

 

• can have Nausea, Vomit, Diarrhea, loss of appetite, stool thin and gastrointestinal ulcers and other gastrointestinal reactions. Occasional epistaxis, menorrhagia, dysmenorrhea and uterine bleeding. Severe liver and kidney disease or blood coagulation insufficiency should not be used.
• the patient was sealed from light and kept in a cool place.

 

Chemical properties	bromelain is a proteolytic enzyme extracted from pineapple juice or pineapple waste skin. It is a light yellow amorphous powder. Slightly soluble in water, insoluble in ethanol, acetone, chloroform, ether. The optimum pH was 7. Slightly abnormal odor. Enzyme activity can be activated by bovine cystine, and by heavy metal inhibition. Preparation of pineapple enzyme enteric-coated tablets, remove the casing after gray-brown. The compound pineapple enzyme tablet is an enteric-coated tablet of pineapple enzyme and pig bile extract powder, which is gray-brown after removing the enteric coating.
Use	bromelain is commonly used in bronchitis, bronchial asthma, acute Pneumonia, postpartum breast hemorrhage, mastitis, postpartum venous thrombosis, retinitis, etc. Various causes of inflammation, edema and hematoma thrombosis. Combined with antibacterial drugs to treat arthritis, periarthritis, cellulitis, leg ulcers, various inflammation of the respiratory system and urinary tract infection. But after taking medicine, gastrointestinal reactions such as: Nausea, Ah vomiting, Diarrhea, loss of appetite, stool thin and digestive tract ulcers. Occasional epistaxis, menorrhagia, dysmenorrhea and uterine bleeding. Tablets should be swallowed, not chewable, so as not to be destroyed by pepsin and failure. Severe liver, kidney disease, is using anticoagulant or blood coagulation bacteria can not be used. The pineapple peel was washed by oral administration, and the juice was squeezed out through the Juice Extractor. 0.5g (I. E. 0.05%) of sodium benzoate was added to each liter of skin juice, which was sent to the raw material warehouse for storage at low temperature. Boropicrin sodium benzoate → press juice adsorption, elution the juice is placed in a stainless steel flask, under constant stirring, and the rotation speed is 40 ~ 60r/min, add 40g (I. E. 4%) per liter of juice the white clay, at the temperature of 100C, adsorption 15~20min, static recognition. The next day, the white clay was allowed to settle well, siphon, remove the supernatant, and leave the wet clay. Add sodium carbonate saturated solution or sodium oxyfluoride (66g/L = 6.6%) to adjust the pH value to 6.5~6~7. 50% ammonium sulfate or edible refined salt based on wet soil is further added, and the mixture is stirred for 25-30min to elute the eluate, and the eluate is pressure-filtered with a filter press to obtain a pressure-filtered solution. Juice white clay; 100 → adsorption adsorption Na2CO3;(NH4)^ 2SO4 → ^ elution; Pressure filter pressure filter solution salting out, suction filter pressure filter solution into the steel drum, adjust to pH 4.5~5 with 9% hydrochloric acid, and add 200 ~ 20% G (25% ~) Ammonium sulfate (or add 250g refined salt) to each liter of this filtrate with gentle agitation with a wooden stick. Salting out was performed to dissolve ammonium sulfate (refined salt) and put into a cold storage. The next day, the upper layer of ammonium sulfate solution was siphoned out, and the lower layer precipitated dilute enzyme paste, which was centrifuged, Crude enzyme paste was obtained. Part of the ammonium sulfate solution was removed by Suction filtration through a Buchner funnel. -20%<0 storage, to be refined. Eluent HCl;((NH4)^ 2 ^)SO4 → Salting out; Suction filtration crude product dissolution, precipitation enzyme crude product into 8~10 times the amount of tap water, then, 160g(16%) of sodium hydroxide was added to each liter of the aqueous solution of the crude enzyme to adjust the pH to 7-75, and the mixture was gently stirred until dissolved. In order to prevent foaming, rapid pressure filtration, separation and removal of impurities, to clear liquid. The pipe and filter press shall be washed with a small amount of tap water, and the washing liquid and the clarified liquid shall be combined. Under constant stirring, pH 4 was adjusted with 9% hydrochloric acid, and the enzyme was precipitated and centrifuged to obtain a wet bromelain product. Tap water of crude product; PH 7~7.5 → dissolved clear liquid HCl; PH 4 → precipitated refined product; Dry and pulverize the wet enzyme fine product; Suction filtration, which causes cracks in filter cake. The filter cake is semi-dried, and some water is removed, vacuum drying, and then grinding by ball mill, bromelain product was obtained. Calculated according to the mass of pineapple, the yield was 0.3725g/ton, and the content was 300,000 F in units/g. Oral, 3-100,000 units/time, 3-4 times/day. External application of 0.1% ~ 0.2% saline solution, for necrotic tissue more wounds and chronic ulcers. Pineapple enzyme enteric-coated tablets. Oral 1~3 tablets, 3~4 times a day, compound pineapple enzyme tablets; Oral 2~4 tablets, 3 times a day.
production method	Press the pineapple peel is washed, and the juice is extracted through the juice extractor, 0.5g (I. E., 0.05%) of sodium benzoate was added to each liter of skin juice as a preservative and sent to the raw material warehouse for cold storage. Boropicrin sodium benzoate → press juice adsorption, elution the juice is placed in a stainless steel flask, under constant stirring, and the rotation speed is 40 ~ 60r/min, add 40g (I. E. 4%) per liter of juice the white clay, at the temperature of 100C, adsorption 15~20min, static recognition. The next day, the white clay was allowed to settle well, siphon, remove the supernatant, and leave the wet clay. Add saturated sodium carbonate solution or sodium oxyfluoride (66g/L, 6.6%) to adjust pH 6.5~7, then add 50% ammonium sulfate or edible salt based on wet soil, stir for 25~30min, The eluent is obtained, and the eluent is pressure-filtered with a filter press to obtain a pressure-filtered liquid. Juice white clay; 100 → adsorption adsorption Na2CO3;(NH4)^ 2SO4 → ^ elution; Pressure filter pressure filter solution salting out, suction filter pressure filter solution into the steel drum, adjust to pH 4.5~5 with 9% hydrochloric acid, and add 200 ~ 20% G (25% ~) Ammonium sulfate (or add 250g refined salt) to each liter of this filtrate with gentle agitation with a wooden stick. Salting out was performed to dissolve ammonium sulfate (refined salt) and put into a cold storage. The next day, the ammonium sulfate solution in the upper layer was siphled out, and the lower layer precipitated dilute enzyme paste, which was centrifuged to obtain crude enzyme paste. Part of the ammonium sulfate solution was removed by Suction filtration through a Buchner funnel. -20%<0 storage, to be refined. Eluent HCl;(NH4) ^ 2 ^)SO4 → Salting out; The crude product was filtered to dissolve and precipitate. The crude enzyme was added to 8-10 times the amount of tap water, and then 160g(16%) was added to the aqueous solution of the crude enzyme per liter. Sodium hydroxide was adjusted to pH 7-75 and gently stirred until dissolved. In order to prevent foaming, rapid pressure filtration, separation and removal of impurities, to clear liquid. The pipe and filter press shall be washed with a small amount of tap water, and the washing liquid and the clarified liquid shall be combined. Under constant stirring, pH 4 was adjusted with 9% hydrochloric acid, and the enzyme was precipitated and centrifuged to obtain a wet bromelain product. Tap water of crude product; PH 7~7.5 → dissolved clear liquid HCl; PH 4 → precipitated refined product; Dry and pulverize the wet enzyme fine product; Suction filtration, which causes cracks in filter cake. The filter cake is semi-dried, and some water is removed, vacuum drying, and then grinding by ball mill, bromelain product was obtained. Calculated according to the mass of pineapple, the yield was 0.3725g/ton, and the content was 300,000 F in units/g. Drying of refined products; Grinding → finished products

Packing:  
  1. Inner double plastic bags----25kg/Fiber drum (35*35*45cm, GW: 28kg, NW: 25kg); 

  2. Inner double plastic bags----5kg/Aluminum foil bag (GW: 6.5kg, NW: 5kg). 

  3. Inner double plastic bags----1kg/Aluminum foil bag (GW: 1.5kg, NW: 1kg). 

P.S.: we accept packaging customization. 

  
Delivery:   

  1. Stock products are normally shipping within 3 working days.  

  2. For rush delivery, please contact our sales team for particular arrangement. 

Shipping Details: 
  1. We ship goods via DHL, Fedex, UPS, TNT, China post, NL Post and other couriers, weight from 10g to 1000kg or even bulker. 

  2. Shipping details & shipping documents will be provided and sent by email. 

  3. We keep tracking the shippment until clients well received. 

  4. After years export shipping experience, with professional and experienced cooperated forwarders, we ensure that goods can be delivered in multiple ways safetly and efficiently. 

About us

Our company specializes in processing and selling chemical raw materials, chemical products, pharmaceutical intermediates, veterinary medicine intermediates, dye intermediates, pigments, cosmetics raw materials and chemical reagents,  

We have compalete sales and service team , information feedback vertical integration of a sound marketing network, products are sold throughout the country and exported to South Asia, Europe, America, Africa and other more than 20 countries and regions.  

Companies adhering to the "pursuit of quality, innovation and development" business philosophy, to serve as a foundation, for the survival by the quality, seek development by science and technology, adhere to quilty comes first,fair price,good sense of customer service and responsibility. in the future hebei Nengqian import and export trade Co.,Ltd will always hold "integrity, innovation" business philosophy, to achieve honesty management, on the way of specialization, internationalization,  Keep moving!  

 

FAQ: 
1. Are you a trade company or factory   
We are a  factory with our own trading company.  

2.How do you control the quality   
Our factory is equipped with professional technicians to control quality, out inspectors take sample for testing every 2 hours to ensure the quality of our production. We also accept BV, SGS or any other Third-party inspection.   

3. How long is lead time   
We deliver goods within 3 days for small order, 7-10 days for bulk order.   

4. Where is your factory located  How can I visit the factory   
 Our factory located in HEBEI, China.

5. Can i get some samples  
  Yes, we can supply free sample, but the shipping cost be paid by our customers. 

6. How to start orders or make payments  
  Proforma invoice will be sent first after confirmation of order, enclosed our bank information.Payment by T/T,  

7. How to confirm the Product Quality before placing orders  
  You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. 
  You can send us your product specifications and requests,we will manufacture the products according to your requests. 

8. How long is lead time

We deliver goods within 3 days for small order, 7-10 days for bulk order.

 

9. How do you treat quality complaint

  First of all, our quality control will reduce the quality problem to near zero. If there is a realquality problem caused by us, we will send you free goods for replacement or refund your loss.