NAD

Details:

 

High Purity 99% NAD powder β-Nicotinamide adenine dinucleotide CAS: 53-84-9

Product Name: β-Nicotinamide adenine dinucleotide

CAS: 53-84-9

MF: C21H27N7O14P2

MW: 663.43

EINECS: 200-184-4

 

β-Nicotinamide adenine dinucleotide Chemical Properties

Melting point 140-142 °C (decomp)

alpha D20 -31.5° (c = 1.2 in water)

storage temp. -20°C

solubility H2O: 50 mg/mL

form Powder

color White

PH ~3.0 (50mg/mL in water)

Odor Odorless

Water Solubility Soluble in water at 50mg/ml

Merck 14,6344

BRN 3584133

Stability: Stable. Hygroscopic. Incompatible with strong oxidizing agents.

 

Application

β-Nicotinamide adenine dinucleotide (β-NAD) is a cofactor of alcohol dehydrogenase and acts as a neuromodulator and an inhibitory neurotransmitter in visceral smooth muscles. The NAD/NADH ratio has a role in the regulation of intracellular redox potential. It thereby influences metabolic reactions in vivo. It has been used for the preparation of deacetylated tubulin. It has also been used for UDP-glucose-6-hydrogenase (UGDH) enzyme activity assay of orital fibroblast cell lysates.

β-Nicotinamide adenine dinucleotide (NAD+) and β-Nicotinamide adenine dinucleotide, reduced (NADH) comprise a coenzyme redox pair (NAD+:NADH) involved in a wide range of enzyme catalyzed oxidation reduction reactions. In addition to its redox function, NAD+/NADH is a donor of ADP-ribose units in ADP-ribosylaton (ADP-ribosyltransferases; poly(ADP-ribose) polymerases ) reactions and a precursor of cyclic ADP-ribose (ADP-ribosyl cyclases).