(2E)-N-{4-[(3-chloro-4-fluorophenyl)amino]-7-(tetrahydrofuran-3-yloxy)quinazolin-6-yl}-4-(dimethylamino)but-2-enamide

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1 Kilogram	FOB Price: USD 1.0000

1 Kilogram

FOB Price: USD 1.0000

(2E)-N-{4-[(3-chloro-4-fluorophenyl)amino]-7-(tetrahydrofuran-3-yloxy)quinazolin-6-yl}-4-(dimethylamino)but-2-enamide Afatinib CAS:439081-18-2

Name: (2E)-N-{4-[(3-chloro-4-fluorophenyl)amino]-7-(tetrahydrofuran-3-yloxy)quinazolin-6-yl}-4-(dimethylamino)but-2-enamide

CAS:439081-18-2

MF: C24H25ClFN5O3

Item	Standard		Test Results
Identification	A.H-NMR:Comply with the structure		Complies
	B.LC-MS:Comply with the structure		Complies
	C.The IR spectrum of sample should be identical with that of reference standard;		Complies
	D.HPLC-ESI-MS		Complies
	The retention time of the major peak in the chromatogram of the Assay preparation corresponds to that in the chromatogram of the Standard preparation, as obtained in the Assay.
Heavy metals	≤10 ppm		<10ppm
Water	≤1.0%		0.10%
Sulphated ash	≤0.5%, determined on 1.0 g.		0.01%
Related substances	Unspecified impurities: for each impurity	≤0.10%	<0.10%
	Total Impurity	≤0.5%	0.18%
Purity	≥99.0%		99.70%
Assay	99.0%~101.0% (anhydrous substance).		99.80%
Storage	Preserve in well-closed, light-resistant and airtight containers.		Complies

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