S-Adenosyl-L-methionine sulfate tosylate

Details:

Product Information

 

 

Product name	S-Adenosyl-L-methionine Disulfate Tosylate/ SAMe
CAS No.	97540-22-2
Molecular Formula	C15H22N6O5S.2(H2SO4).C7H8SO3
Molecular Weight	766,79
Quality Standard	95%-103% by HPLC, USP43
Appearance	White to off-white powder

 

 

 

COA

 

 

ANALYSIS	SPECIFICATION	RESULTS
Appearance	White to off-white Powder	White to off-white Powder
Identification:
Infrared	Conforms to the Reference Spectrum		Complied
HPLC	The retention time of the major peak corresponds to the reference sample		Complied
Water Content(K.F)	3.0% MAX		1.2%
Sulphated Ash	0.5% MAX.		0.3%
PH (5% AQUEOUS SOLUTION)	1.0 -2.0		1.2
S, S-Isomer (HPLC)	75.0% MIN		82.4%
SAM-e ION (HPLC)	49.5 - 54.7%		51.5%
P-Toluenesulfonic Acid	21.0%–24.0%		22.5%
Content of Sulfate (SO4) (HPLC)	23.5%–26.5%		25.0%
S-Adenosyl-L-methionine Disulfate Tosylate 95.0%–103%	95.0%-103.0%		99.0%
Related substances(HPLC):
-S-ADENOSYL-L-HOMOCYSTEINE	1.0% MAX.		0.17%
- ADENINE	1.0% MAX.		0.26%
- METHYLTHIOADENOSINE	1.5% MAX		0.17%
- ADENOSINE	1.0% MAX.		0.07%
- TOTAL IMPURITIES	3.5% MAX.		1.1%
Heavy Metals	Not more than 10 ppm		Complied
LEAD	Not more than 3 ppm		Complied
CADMIUM	Not more than 1 ppm		Complied
MERCURY	Not more than 0.1 ppm		Complied
ARSENIC	Not more than 2 ppm		Complied
Micorbiology:
Total Aerobic Count	≤1000cfu/g		Complies
Yeast and mold count	≤100cfu/g		Complies
Microbiology E. coli	Absent/10g		Complies
S. aureus	Absent/10g		Complies
Salmonella	Absent/10g		Complies
Conclusion	Complies with USP43

 

 

Usage

 

S-Adenosyl-L-methionine Disulfate Tosylate has a wide range of applications due to its unique biological properties.

1. As a Food Supplement

    S-Adenosyl-L-methionine Disulfate Tosylate is a form of S-adenosyl-L-methionine (SAMe), which is a naturally occurring compound found in the body. It serves as a methyl donor in biochemical reactions and is involved in various metabolic processes. As a dietary supplement, it is used to support liver health, improve mood and cognitive function, and reduce pain and inflammation associated with osteoarthritis.

2. Antidepressant

    Clinical studies have shown that S-adenosyl-L-methionine (SAMe) has antidepressant effects. It works by increasing the levels of neurotransmitters such as serotonin and dopamine in the brain, which are involved in regulating mood and emotional responses. S-Adenosyl-L-methionine Disulfate Tosylate, as a stable form of SAMe, can be used as an alternative treatment for depression, especially in cases where traditional antidepressants are not effective or cause side effects.

3. Research in Liver Disease and Osteoarthritis

    S-Adenosyl-L-methionine has been extensively studied in the context of liver disease and osteoarthritis. In liver disease, it has been shown to improve liver function and reduce liver damage caused by various factors such as alcohol, drugs, and viruses. In osteoarthritis, it has been found to reduce pain and inflammation, and improve joint function. S-Adenosyl-L-methionine Disulfate Tosylate, as a stable and effective form of SAMe, can be used in research to further explore its potential therapeutic effects in these areas.

4. Other Potential Uses

    In addition to the above-mentioned uses, S-Adenosyl-L-methionine Disulfate Tosylate may also have other potential applications. For example, it may be used to support cognitive function and reduce the risk of neurodegenerative diseases such as Alzheimer's disease. However, more research is needed to confirm these potential uses and their efficacy.

 

Sinoway’s advantage:

 

The production of S-Adenosyl-L-methionine Disulfate Tosylate in China uses a unique enzymatic engineering innovation platform, which has overcome several technical challenges in the enzymatic synthesis of adenosine methionine. Successfully, a novel production technology for adenosine methionine using solid-phase enzymatic synthesis has been developed, and patents have been successfully applied for in China, the United States, and the European Union. Compared to the current most advanced fermentation production technology globally, this novel solid-phase enzymatic synthesis process and technology for producing adenosine methionine offers significant investment and competitive advantages, including low energy consumption, low pollution, lower investment costs, higher quality, and lower production costs.