2-Anthracenecarboxylic acid, 4,5-bis(acetyloxy)-9,10-dihydro-9,10-dioxo- (9CI) 4,5-diacetyloxy-9,10-dioxo-anthracene-2-carboxylic acid 4,5-Bis(acetyloxy)-9,10-dihydro-9,10-dioxo-2-anthracenecarboxylic acid
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Quick details of Diacerein powder
product name: Diacerein
Alias: 1,8-DIACETOXY-3-CARBOXYANTHRAQUINONE;DIACEREIN;DIACERHEIN;DIACETYLRHEIN;9,10-dihydro-4,5-diacetoxy-9,10-2-anthracenecarboxylicacid;Chemicalbook9,10-dihydro-4,5-dihydroxy-9,10-dioxo-2-anthroicaciddiacetate;9,10-dihydro-4,5-dihydroxy-9,10-dioxo-2-anthroicacidiacetate;artrodar;
CAS.No: 13739-02-1
Appearance:Light yellow to thick yellow solid
Molecular formula: C19H12O8
Molecular weight: 368.29
EINECS.No: 237-310-2
melting point: 217-218℃
boiling point: 631.5±55.0 °C
density: 1.491±0.06 g/cm3
storage condition: Sealed in dry,Room Temperature
solubility: DMSO (a small amount), methanol (a small amount)
Acidity coefficient (pKa): 3.01±0.20
water solubility: 240μg/L at 25℃
payment methods:,T/T
shipping methods: EMS,TNT,FedEx,DHL,UPS;
What is Diacerein?
Diacerein is an osteoarthritis IL-1 factor inhibitor, mainly used to treat degenerative joint diseases, and can improve symptoms such as pain and joint dysfunction caused by osteoarthritis and related diseases.
It inhibits the production and activity of IL-1, inhibits the inflammatory cascade from the source, and relieves inflammation and pain. In addition, by inhibiting IL-1 and stimulating the expression of transforming growth factor (TGF-β), it promotes the synthesis of collagen and proteoglycans, and then promotes cartilage synthesis.
By inhibiting IL-1, it inhibits subchondral bone hyperplasia and delays disease progression.
Other uses of diacerein
1. Rheumatoid arthritis
2. Ankylosing spondylitis
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