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Tauroursodeoxycholic acid 14605-22-2 Tauroursodeoxycholic acid in stock
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Hebei Mojin Biotechnology Co., Ltd, Our company is a professional chemical raw materials and chemical reagents research and development production enterprises. Our business covers more than 30 countries, most of the big customers come from Europe, America and other countries in the world, we can guarantee the quality and price. In recent decades, with the efforts of all employees, we have established many cooperative companies in shandong, henan, guangdong and other places. Our corporate purpose is based on the market, enhance the strength, take the road of scientific and environmental sustainable development, relying on the country. Technology r & d center, increase the investment in r & d, based on the domestic market, expand the international market, manufacturing quality products, sincere service to the society, into a modern, ecological, scientific and technological enterprise world.
Product Information
Tauroursodeoxycholic acid CAS:14605-22-2 With high Purity
Product Name:Tauroursodeoxycholic acid
Synonyms:ursodeoxycholyltaurine;yl)amino)-;3a,7b-Dihydroxy-5b-cholan-24-oic Acid N-(2-Sulfoethyl)amide;Ursodeoxycholyltaurin;3α,7β-dihydroxy-5β-cholan-24-oic acid n-(2-sulfoethyl)amide;TUDCA Soduim Salt;TAUROURSODEOXYCHOLIC ACID DIHYDRATE: 90%;tauroursodeoxycholic acid sodium
CAS:14605-22-2
MF:C26H45NO6S
MW:499.7
EINECS: 1308068-626-2
Melting point:173-175°C
density:1.216±0.06 g/cm3(Predicted)
refractive index:46 ° (C=1, EtOH)
storage temp.:15-25℃
solubility:Soluble in DMSO (up to 30 mg/ml) or in Ethanol (up to 20 mg/ml with warming)
Stability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
Chemical Properties:Tauroursodeoxycholic acid is an off-White Solid. It is an ambiphilic bile acid. It is mainly found in black bear bile, which is the signature active ingredient in bear bile. It has antispasmodic, anticonvulsant, anti-inflammatory and gallstone dissolving effects.
Description
Tauroursodeoxycholic acid (TUDCA) is a hydrophilic bile acid synthesized in hepatocytes by the conjugation of ursodeoxycholic acid (UDCA) with the amino acid taurine. UDCA, which is made by gut bacteria, is FDAapproved in the United States for the treatment of certain cholestatic liver diseases. Humans make TUDCA to some extent, but it is found in copious amounts in the bile of bears. TUDCA is a classic inhibitor of endoplasmic reticulum (ER) stress. Reduces ER stress and adipose tissue inflammation in a mouse model of high fat diet-induced obesity. Blocks ER stress-induced NLRP3 inflammasome activation and hepatocyte death. Attenuates amyloid precursor protein processing and amyloid-β deposition in APP/PS1 mouse model.
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Company Information
Hebei Mojin Biotechnology Co., Ltd, our business covers more than 30 countries, most of the big customers come from Europe, America and other countries in the world, we can guarantee the quality and price. In recent decades, with the efforts of all employees, we have established many cooperative companies in shandong, henan, guangdong and other places. Our corporate purpose is based on the market, enhance the strength, take the road of scientific and environmental sustainable development, relying on the country. Technology r & d center, increase the investment in r & d, based on the domestic market, expand the international market, manufacturing quality products, sincere service to the society, into a modern, ecological, scientific and technological enterprise world.
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