Cys-MC-MMAF

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Purity: ≥95%

Keywords

L-Phenylalanine, N-[6-[3-[[(2R)-2-amino-2-carboxyethyl]thio]-2,5-dioxo-1-pyrrolidinyl]-1-oxohexyl]-N-methyl-L-valyl-L-valyl-(3R,4S,5S)-3-methoxy-5-methyl-4-(methylamino)heptanoyl-(αR,βR,2S)-β-m... N-[6-[3-[[(2R)-2-Amino-2-carboxyethyl]thio]-2,5-dioxo-1-pyrrolidinyl]-1-oxohexyl]-N-methyl-L-valyl-L-valyl-(3R,4S,5S)-3-methoxy-5-methyl-4-(methylamino)heptanoyl-(αR,βR,2S)-β-methoxy-α-methyl-...

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Appearance:Solid
Application:For research use only.
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Storage:Store at -20°C, protect from light
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Details:

Cys-MC-MMAF is the released payload of AlMcMMAF, an anti-5T4 humanized A1 antibody that is conjugated to microtubule MMAF destruction via a maleimidocaproyl linker. It has antitumor effects on two tumor mouse models (H1975 and MDA-MB-361-DYT2).

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