Duocarmycin DM

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Purity: 95%

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(S)-(1-(chloromethyl)-5-hydroxy-1,2-dihydro-3H-benzo[e]indol-3-yl)(5-(2-(dimethylamino)ethoxy)-1H-indol-2-yl)methanone TFA

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Duocarmycin DM is a DNA minor-groove alkylating agent, which can be used as an antibody drug conjugate (ADC) toxin. Duocarmycin DM is based on its characteristic curved indole structure and a spirocyclopropylcyclohexadienone electrophile to act anticancer

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