Gap 26

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Purity: 98%

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H-Val-Cys-Tyr-Asp-Lys-Ser-Phe-Pro-Ile-Ser-His-Val-Arg-OH L-valyl-L-cysteinyl-L-tyrosyl-L-alpha-aspartyl-L-lysyl-L-seryl-L-phenylalanyl-L-prolyl-L-isoleucyl-L-seryl-L-histidyl-L-valyl-L-arginine

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Appearance:Powder
Application:For research use only.
PackAge:10 mg
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Storage:Store at -20°C
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Gap 26 is a gap junction blocker which is corresponding to residues 63 - 75 of connexin 43. Gap 26 was shown to attenuate rhythmic contractile activity of rabbit arterial smooth muscle (IC50 = 28.4 μM). It also inhibits IP3-induced ATP release but does not inhibit gap junctional coupling in endothelial cells.

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