NEP1-40 Nogo Extracellular Peptide, 1-40
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Nogo-66 (1-40), a peptide fragment corresponding to residues 1-40 of Nogo-66, acts as a competitive antagonist at the Nogo-66 receptor (NgR), which blocks Nogo-66 or CNS myelin inhibition of axonal outgrowth in vitro, demonstrating that NgR mediates a significant portion of axonal outgrowth inhibition by myelin.
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